Extracellular vesicles as a next-generation drug delivery platform
IK Herrmann, MJA Wood, G Fuhrmann - Nature nanotechnology, 2021 - nature.com
Extracellular-vesicle-based cell-to-cell communication is conserved across all kingdoms of
life. There is compelling evidence that extracellular vesicles are involved in major (patho) …
life. There is compelling evidence that extracellular vesicles are involved in major (patho) …
Exosome: a review of its classification, isolation techniques, storage, diagnostic and targeted therapy applications
Y Zhang, J Bi, J Huang, Y Tang, S Du… - International journal of …, 2020 - Taylor & Francis
Exosomes are nano-sized small extracellular vesicles secreted by cells, carrying nucleic
acids, proteins, lipids and other bioactive substances to play a role in the body's …
acids, proteins, lipids and other bioactive substances to play a role in the body's …
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …
origin and change the functions and phenotypes of other cells. These features indicate …
Identification of storage conditions stabilizing extracellular vesicles preparations
Extracellular vesicles (EVs) play a key role in many physiological and pathophysiological
processes and hold great potential for therapeutic and diagnostic use. Despite significant …
processes and hold great potential for therapeutic and diagnostic use. Despite significant …
The impact of storage on extracellular vesicles: A systematic study
S Gelibter, G Marostica, A Mandelli… - Journal of …, 2022 - Wiley Online Library
Mounting evidence suggests that storage has an impact on extracellular vesicles (EVs)
properties. While− 80° C storage is a widespread approach, some authors proposed …
properties. While− 80° C storage is a widespread approach, some authors proposed …
[HTML][HTML] Exosome nanovesicles: a potential carrier for therapeutic delivery
Exosomes are small nanosized biovesicles that form when multivesicular bodies and the
plasma membrane fuse and are released into the surrounding body fluids. They are best …
plasma membrane fuse and are released into the surrounding body fluids. They are best …
Technology insight: Plant-derived vesicles—How far from the clinical biotherapeutics and therapeutic drug carriers?
M Cong, S Tan, S Li, L Gao, L Huang, HG Zhang… - Advanced drug delivery …, 2022 - Elsevier
Within the past decades, extracellular vesicles (EVs) have emerged as important mediators
of intercellular communication in both prokaryotes and higher eukaryotes to regulate a …
of intercellular communication in both prokaryotes and higher eukaryotes to regulate a …
Challenges in the development and establishment of exosome-based drug delivery systems
J Wang, D Chen, EA Ho - Journal of Controlled Release, 2021 - Elsevier
Exosomes are extracellular vesicles released from cells and are characterized by a lipid
bilayer membrane encapsulating a variety of biological molecules such as nucleic acids or …
bilayer membrane encapsulating a variety of biological molecules such as nucleic acids or …
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the …
C Théry, KW Witwer, E Aikawa… - Journal of …, 2018 - Wiley Online Library
The last decade has seen a sharp increase in the number of scientific publications
describing physiological and pathological functions of extracellular vesicles (EVs), a …
describing physiological and pathological functions of extracellular vesicles (EVs), a …
Immunogenicity of extracellular vesicles
Extracellular vesicles (EVs) are promising next‐generation therapeutics and drug delivery
systems due to demonstrated safety and efficacy in preclinical models and early‐stage …
systems due to demonstrated safety and efficacy in preclinical models and early‐stage …