Mechanotransduction couples mechanical stimulation with ion flux, which is critical for
normal biological processes involved in neuronal cell development, pain sensation, and red …

Activation of mechanosensitive ion channels underlies a variety of fundamental
physiological processes that require sensation of mechanical force. Different …

Mechanosensation is the ability to detect dynamic mechanical stimuli (eg, pressure, stretch,
and shear stress) and is essential for a wide variety of processes, including our sense of …

Many ion channels have been described as mechanosensitive according to various criteria.
Most broadly defined, an ion channel is called mechanosensitive if its activity is controlled by …

Mechanosensitive ion channels rely on membrane composition to transduce physical stimuli
into electrical signals. The Piezo1 channel mediates mechanoelectrical transduction and …

The conversion of force into an electrical cellular signal is mediated by the opening of
different types of mechanosensitive ion channels (MSCs), including TREK/TRAAK K 2P …

Piezo1 is a member of the mechanosensitive piezo ion channel family, which transduces
various mechanical stimulations into electrochemical signals. Piezo1 is closely implicated in …

Gastrointestinal enterochromaffin cells regulate bone and gut homeostasis via serotonin (5-
hydroxytryptamine [5-HT]) production. A recent report suggested that gut microbes regulate …

Mechanotransduction, the conversion of mechanical stimuli into electrical signals, is a
fundamental process underlying essential physiological functions such as touch and pain …

The sense of touch is fundamental as it provides vital, moment-to-moment information about
the nature of our physical environment. Primary sensory neurons provide the basis for this …