The PRIMED Consortium: Reducing disparities in polygenic risk assessment
IJ Kullo, MP Conomos, SC Nelson… - The American Journal of …, 2024 - cell.com
By improving disease risk prediction, polygenic risk scores (PRSs) could have a significant
impact on health promotion and disease prevention. Due to the historical oversampling of …
impact on health promotion and disease prevention. Due to the historical oversampling of …
Variability in performance of genetic-enhanced DXA-BMD prediction models across diverse ethnic and geographic populations: A risk prediction study
Background Osteoporosis is a major global health issue, weakening bones and increasing
fracture risk. Dual-energy X-ray absorptiometry (DXA) is the standard for measuring bone …
fracture risk. Dual-energy X-ray absorptiometry (DXA) is the standard for measuring bone …
Validation of GenProb‐T1D and its clinical utility for differentiating types of diabetes in a biobank from a US healthcare system
Atypical diabetes with overlap** clinical features of type 1 (T1D) and type 2 (T2D) is
common and challenging diagnostically and for implementing effective treatment. Here, we …
common and challenging diagnostically and for implementing effective treatment. Here, we …
Artificial Intelligence Applications in Genomics
R Nagarajan, C Wang… - Advances in …, 2024 - advancesinmolecularpathology.com
Several factors have contributed to the rapid growth of genomic data, including the
significant reduction in high-throughput sequencing costs, the availability of scalable and …
significant reduction in high-throughput sequencing costs, the availability of scalable and …