Microfluidic cell cultures are ideally positioned to become the next generation of in vitro
diagnostic tools for biomedical research, where key biological processes such as cell …

A biosensor is an analytical device that can be used for detecting analytes and combines a
biological component with a physicochemical detecting transducer. In recent years …

This paper presents a chip-based electrophysiological platform enabling the study of micro-
and macro-circuitry in in-vitro neuronal preparations. The approach is based on a 64× 64 …

Microelectrode arrays (MEAs) provide promising opportunities to study electrical signals in
neuronal and cardiac cell networks, restore sensory function, or treat disorders of the …

Human pluripotent stem cell (hPSC)-derived neuron cultures have emerged as models of
electrical activity in the human brain. Microelectrode arrays (MEAs) measure changes in the …

Neurons extracted from specific areas of the Central Nervous System (CNS), such as the
hippocampus, the cortex and the spinal cord, can be cultured in vitro and coupled with a …

Complex network topologies represent the necessary substrate to support complex brain
functions. In this work, we reviewed in vitro neuronal networks coupled to Micro-Electrode …

This study investigated a novel multi-electrode-array (MEA) design capable of long-term and
highly selective recordings of axonal signals using PDMS microtunnels. We successfully …

The development of microelectrode arrays (MEAs) along with complementary advances in
electronics, mechanics and software to connect with these arrays has led to the in vitro …

The interplay between anatomical connectivity and dynamics in neural networks plays a key
role in the functional properties of the brain and in the associated connectivity changes …