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SABRE: Chemical kinetics and spin dynamics of the formation of hyperpolarization
In this review, we present the physical principles of the SABRE (Signal Amplification By
Reversible Exchange) method. SABRE is a promising hyperpolarization technique that …
Reversible Exchange) method. SABRE is a promising hyperpolarization technique that …
Recent advances in the application of parahydrogen in catalysis and biochemistry
G Buntkowsky, F Theiss, J Lins, YA Miloslavina… - RSC …, 2022 - pubs.rsc.org
Nuclear Magnetic Resonance (NMR) spectroscopy and Magnetic Resonance Imaging (MRI)
are analytical and diagnostic tools that are essential for a very broad field of applications …
are analytical and diagnostic tools that are essential for a very broad field of applications …
In Vivo Metabolic Imaging of [1‐13C]Pyruvate‐d3 Hyperpolarized By Reversible Exchange With Parahydrogen**
Metabolic magnetic resonance imaging (MRI) using hyperpolarized (HP) pyruvate is
becoming a non‐invasive technique for diagnosing, staging, and monitoring response to …
becoming a non‐invasive technique for diagnosing, staging, and monitoring response to …
Over 20% carbon-13 polarization of perdeuterated pyruvate using reversible exchange with parahydrogen and spin-lock induced crossing at 50 μT
Carbon-13 hyperpolarized pyruvate is about to become the next-generation contrast agent
for molecular magnetic resonance imaging of cancer and other diseases. Here, efficient and …
for molecular magnetic resonance imaging of cancer and other diseases. Here, efficient and …
LIGHT-SABRE Hyperpolarizes 1-13C-Pyruvate Continuously without Magnetic Field Cycling
AN Pravdivtsev, K Buckenmaier, N Kempf… - The Journal of …, 2023 - ACS Publications
Nuclear spin hyperpolarization enables real-time observation of metabolism and
intermolecular interactions in vivo. 1-13C-pyruvate is the leading hyperpolarized tracer …
intermolecular interactions in vivo. 1-13C-pyruvate is the leading hyperpolarized tracer …
In Situ Hyperpolarization Enables 15N and 13C Benchtop NMR at Natural Isotopic Abundance
Without employing isotopic labeling, we demonstrate the generation of 15N and 13C NMR
signals for molecules containing− NH2 motifs using benchtop NMR spectrometers (1–1.4 T) …
signals for molecules containing− NH2 motifs using benchtop NMR spectrometers (1–1.4 T) …
Parahydrogen-based NMR signal amplification by reversible exchange (SABRE): Recent advances and applications
Signal amplification by reversible exchange (SABRE) is a rapidly develo** nuclear
magnetic resonance (NMR) hyperpolarization technique utilizing parahydrogen for dramatic …
magnetic resonance (NMR) hyperpolarization technique utilizing parahydrogen for dramatic …
Synergies between hyperpolarized NMR and microfluidics: A review
Hyperpolarized nuclear magnetic resonance and lab-on-a-chip microfluidics are two
dynamic, but until recently quite distinct, fields of research. Recent developments in both …
dynamic, but until recently quite distinct, fields of research. Recent developments in both …
13C MRI of hyperpolarized pyruvate at 120 µT
Nuclear spin hyperpolarization increases the sensitivity of magnetic resonance dramatically,
enabling many new applications, including real-time metabolic imaging. Parahydrogen …
enabling many new applications, including real-time metabolic imaging. Parahydrogen …
Improving SABRE hyperpolarization with highly nonintuitive pulse sequences: Moving beyond avoided crossings to describe dynamics
Signal amplification by reversible exchange (SABRE) creates “hyperpolarization”(large spin
magnetization) using a transition metal catalyst and parahydrogen, addressing the …
magnetization) using a transition metal catalyst and parahydrogen, addressing the …