The role of depressive subtypes within the neuroinflammation hypothesis of major depressive disorder

M Woelfer, V Kasties, S Kahlfuss, M Walter - Neuroscience, 2019‏ - Elsevier
Major depressive disorder (MDD) is a very common disease that affects more than 350
million people worldwide, representing an enormous socioeconomic burden. From a clinical …

Meta-analysis of reward processing in major depressive disorder reveals distinct abnormalities within the reward circuit

TH Ng, LB Alloy, DV Smith - Translational psychiatry, 2019‏ - nature.com
Many neuroimaging studies have investigated reward processing dysfunction in major
depressive disorder. These studies have led to the common idea that major depressive …

Rest to promote learning: a brain default Mode Network Perspective

W Luo, B Liu, Y Tang, J Huang, J Wu - Behavioral Sciences, 2024‏ - mdpi.com
The brain often switches freely between focused attention and divergent thinking, and the
Default Mode Network (DMN) is activated during brain rest. Since its discovery, the DMN …

Task‐induced deactivation dysfunction during reward processing is associated with low self‐esteem in a possible subtype of major depression

AK Jüllig, S Hebib, H Metzker, E Gruber… - Brain and …, 2024‏ - Wiley Online Library
Introduction Low self‐esteem is a frequent symptom in major depressive disorder (MDD).
This functional magnetic resonance imaging study investigated whether MDD patients with …

Default mode network activity in depression subtypes

BJ Borserio, CF Sharpley, V Bitsika… - Reviews in the …, 2021‏ - degruyter.com
Depression continues to carry a major disease burden worldwide, with limitations on the
success of traditional pharmacological or psychological treatments. Recent approaches …

Functional connectivity between the habenula and default mode network and its association with the antidepressant effect of ketamine

M Wang, X Chen, Y Hu, Y Zhou, C Wang… - Depression and …, 2022‏ - Wiley Online Library
Background Recently, an animal model for depression has shown that ketamine, an N‐
methyl‐d‐aspartate receptor (NMDAR) antagonist, elicits a rapid‐acting antidepressant …

Neural signatures of saliency-map** in anhedonia: a narrative review

A Pisoni, SW Davis, M Smoski - Psychiatry research, 2021‏ - Elsevier
Anhedonia is the loss of pleasure or motivation to engage in previously enjoyable activities,
and is a transdiagnostic symptom associated with significant clinical impairment. Anhedonia …

Modeling heterogeneous brain dynamics of depression and melancholia using energy landscape analysis

PR Regonia, M Takamura, T Nakano… - Frontiers in …, 2021‏ - frontiersin.org
Our current understanding of melancholic depression is shaped by its position in the
depression spectrum. The lack of consensus on how it should be treated—whether as a …

Novelty seeking and reward dependence‐related large‐scale brain networks functional connectivity variation during salience expectancy

S Li, LR Demenescu, CM Sweeney‐Reed… - Human brain …, 2017‏ - Wiley Online Library
A salience network (SN) anchored in the anterior insula (AI) and dorsal anterior cingulate
cortex (dACC) plays a key role in switching between brain networks during salience …

Neural divergence between individuals with and without minor depression during dynamic emotion processing: a movie-fMRI Study

M Zhang, M Deng, X Li, R Zhang, J Liao… - Social Cognitive and …, 2024‏ - academic.oup.com
Research on the neuropathological mechanisms underlying minor depression (MD),
particularly in individuals with a history of recurrent minor depressive episodes, is very …