Microbiota succession throughout life from the cradle to the grave

C Martino, AH Dilmore, ZM Burcham… - Nature Reviews …, 2022 - nature.com
Associations between age and the human microbiota are robust and reproducible. The
microbial composition at several body sites can predict human chronological age relatively …

Mass spectrometry-based metabolomics in microbiome investigations

A Bauermeister, H Mannochio-Russo… - Nature Reviews …, 2022 - nature.com
Microbiotas are a malleable part of ecosystems, including the human ecosystem.
Microorganisms affect not only the chemistry of their specific niche, such as the human gut …

MicrobiomeAnalyst 2.0: comprehensive statistical, functional and integrative analysis of microbiome data

Y Lu, G Zhou, J Ewald, Z Pang, T Shiri… - Nucleic Acids …, 2023 - academic.oup.com
Microbiome studies have become routine in biomedical, agricultural and environmental
sciences with diverse aims, including diversity profiling, functional characterization, and …

Multi-level analysis of the gut–brain axis shows autism spectrum disorder-associated molecular and microbial profiles

JT Morton, DM **, RH Mills, Y Shao, G Rahman… - Nature …, 2023 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
heterogeneous cognitive, behavioral and communication impairments. Disruption of the gut …

Standardized multi-omics of Earth's microbiomes reveals microbial and metabolite diversity

JP Shaffer, LF Nothias, LR Thompson, JG Sanders… - Nature …, 2022 - nature.com
Despite advances in sequencing, lack of standardization makes comparisons across studies
challenging and hampers insights into the structure and function of microbial communities …

Machine learning and deep learning applications in microbiome research

R Hernández Medina, S Kutuzova… - ISME …, 2022 - academic.oup.com
The many microbial communities around us form interactive and dynamic ecosystems called
microbiomes. Though concealed from the naked eye, microbiomes govern and influence …

Linking plant secondary metabolites and plant microbiomes: a review

Z Pang, J Chen, T Wang, C Gao, Z Li, L Guo… - Frontiers in plant …, 2021 - frontiersin.org
Plant secondary metabolites (PSMs) play many roles including defense against pathogens,
pests, and herbivores; response to environmental stresses, and mediating organismal …

Integrated analysis of the faecal metagenome and serum metabolome reveals the role of gut microbiome-associated metabolites in the detection of colorectal cancer …

F Chen, X Dai, CC Zhou, K Li, Y Zhang, XY Lou… - Gut, 2022 - gut.bmj.com
Objective To profile gut microbiome-associated metabolites in serum and investigate
whether these metabolites could distinguish individuals with colorectal cancer (CRC) or …

[HTML][HTML] Linear and nonlinear correlation estimators unveil undescribed taxa interactions in microbiome data

H Lin, M Eggesbø, SD Peddada - Nature communications, 2022 - nature.com
It is well-known that human gut microbiota form an ecosystem where microbes interact with
each other. Due to complex underlying interactions, some microbes may correlate …

Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis

RC Brewer, TV Lanz, CR Hale… - Science translational …, 2023 - science.org
Periodontal disease is more common in individuals with rheumatoid arthritis (RA) who have
detectable anti-citrullinated protein antibodies (ACPAs), implicating oral mucosal …