Chalcones have been well examined in the extant literature and demonstrated antibacterial,
antifungal, anti-inflammatory, and anticancer properties. A detailed evaluation of the …

Chalcones are a class of privileged scaffolds with high medicinal significance due to the
presence of an α, β-unsaturated ketone functionality. Numerous functional modifications of …

Chalcones (1, 3-diaryl-2-propen-1-ones) and their heterocyclic analogues, belong to the
flavonoid family, which possess a number of interesting biological properties such as …

Malaria remains a serious worldwide health danger and massive economic trouble to
disease-endemic nations. Presently, 250 million of malarial cases are expected worldwide …

Tuberculosis (TB) is a lift-threatening chronic deadliest infectious disease caused
predominantly by Mycobacterium tuberculosis (MTB) which affects primarily the lungs …

An amphiphilic boron-azadipyrromethene (aza-BODIPY) dye (R)-1 bearing two chiral
hydrophobic side chains was synthesized, and its supramolecular chiral assembly …

A targeted series of chalcone and dienone hybrid compounds containing aminoquinoline
and nucleoside templates was synthesized and evaluated for in vitro antimalarial activity …

New anti-tuberculosis (anti-TB) drugs are urgently needed to battle drug-resistant
Mycobacterium tuberculosis strains and to shorten the current 6–12-month treatment …

The manuscript describes the synthesis of novel 1, 2, 3-triazole tethered β-lactam-chalcone
bifunctional hybrids via click chemistry approach utilizing azide-alkyne cycloaddition …

Indole chalcones were designed and synthesized as a promising set of compounds against
H 37 Rv strain of Mycobacterium tuberculosis. Within this library of compounds,(E)-1-(furan …