[HTML][HTML] Journey to the centre of the lung. The perspective of a mineralogist on the carcinogenic effects of mineral fibres in the lungs

AF Gualtieri - Journal of Hazardous Materials, 2023 - Elsevier
This work reviews the bio-chemical mechanisms leading to adverse effects produced when
mineral fibres are inhaled and transported in the lungs from the perspective of a …

Anthropocene airborne microfibers: Physicochemical characteristics, identification methods and health impacts

Y Cao, L Shao, TP Jones, W Deng, M Santosh… - TrAC Trends in …, 2024 - Elsevier
The toxicity of fibrous particles in ambient air can be higher than that of particles of other
shapes; a phenomenon referred to as the fiber paradigm. Microfibers (MFs) can be classified …

The influence of cation exchange on the possible mechanism of erionite toxicity: A synchrotron-based micro-X-ray fluorescence study on THP-1-derived macrophages …

S Raneri, A Gianoncelli, V Bonanni, S Mirata… - Environmental …, 2024 - Elsevier
Fibrous erionite is the only zeolite classified as Group 1 carcinogen by the International
Agency for Research on Cancer (IARC). Carcinogenesis induced by erionite is thought to …

In vitro acellular dissolution of mineral fibres: A comparative study

AF Gualtieri, S Pollastri, N Bursi Gandolfi… - Scientific Reports, 2018 - nature.com
The study of the mechanisms by which mineral fibres promote adverse effects in both
animals and humans is a hot topic of multidisciplinary research with many aspects that still …

Global geological occurrence and character of the carcinogenic zeolite mineral, erionite: A review

JP Patel, MS Brook, M Kah, A Hamilton - Frontiers in Chemistry, 2022 - frontiersin.org
As with the six regulated asbestos minerals (chrysotile, amosite, crocidolite, anthophyllite,
tremolite, and actinolite), the zeolite mineral, erionite, can exhibit a fibrous morphology …

[HTML][HTML] The acute toxicity of mineral fibres: a systematic in vitro study using different THP-1 macrophage phenotypes

S Mirata, V Almonti, D Di Giuseppe, L Fornasini… - International journal of …, 2022 - mdpi.com
Alveolar macrophages are the first line of defence against detrimental inhaled stimuli. To
date, no comparative data have been obtained on the inflammatory response induced by …

Biodurability and release of metals during the dissolution of chrysotile, crocidolite and fibrous erionite

AF Gualtieri, G Lusvardi, A Zoboli, D Di Giuseppe… - Environmental …, 2019 - Elsevier
Background The mechanisms by which mineral fibers induce adverse effects in vivo are still
not well understood. The mechanisms of fiber dissolution in the lungs and subsequent …

Iron from a geochemical viewpoint. Understanding toxicity/pathogenicity mechanisms in iron-bearing minerals with a special attention to mineral fibers

AF Gualtieri, GB Andreozzi, M Tomatis… - Free Radical Biology and …, 2019 - Elsevier
Iron and its role as soul of life on Earth is addressed in this review as iron is one of the most
abundant elements of our universe, forms the core of our planet and that of telluric (ie, Earth …

Acute cytotoxicity of mineral fibres observed by time-lapse video microscopy

D Di Giuseppe, S Scarfì, A Alessandrini, AM Bassi… - Toxicology, 2022 - Elsevier
Inhalation of mineral fibres is associated with the onset of an inflammatory activity in the
lungs and the pleura responsible for the development of fatal malignancies. It is known that …

Could soluble minerals be hazardous to human health? Evidence from fibrous epsomite

M Giordani, MA Meli, C Roselli, M Betti, F Peruzzi… - Environmental …, 2022 - Elsevier
From a toxicological point of view, particulates and fibres with high solubility in water and/or
in biological environments have not been considered in detail and the knowledge to date in …