Recent advances in predicting protein–protein interactions with the aid of artificial intelligence algorithms

S Li, S Wu, L Wang, F Li, H Jiang, F Bai - Current Opinion in Structural …, 2022 - Elsevier
Protein–protein interactions (PPIs) are essential in the regulation of biological functions and
cell events, therefore understanding PPIs have become a key issue to understanding the …

Cracking the black box of deep sequence-based protein–protein interaction prediction

J Bernett, DB Blumenthal, M List - Briefings in Bioinformatics, 2024 - academic.oup.com
Identifying protein–protein interactions (PPIs) is crucial for deciphering biological pathways.
Numerous prediction methods have been developed as cheap alternatives to biological …

Structure-aware protein–protein interaction site prediction using deep graph convolutional network

Q Yuan, J Chen, H Zhao, Y Zhou, Y Yang - Bioinformatics, 2022 - academic.oup.com
Motivation Protein–protein interactions (PPI) play crucial roles in many biological processes,
and identifying PPI sites is an important step for mechanistic understanding of diseases and …

DELPHI: accurate deep ensemble model for protein interaction sites prediction

Y Li, GB Golding, L Ilie - Bioinformatics, 2021 - academic.oup.com
Motivation Proteins usually perform their functions by interacting with other proteins, which is
why accurately predicting protein–protein interaction (PPI) binding sites is a fundamental …

Benchmark evaluation of protein–protein interaction prediction algorithms

B Dunham, MK Ganapathiraju - Molecules, 2021 - mdpi.com
Protein–protein interactions (PPIs) perform various functions and regulate processes
throughout cells. Knowledge of the full network of PPIs is vital to biomedical research, but …

[HTML][HTML] MM-StackEns: A new deep multimodal stacked generalization approach for protein–protein interaction prediction

AI Albu, MI Bocicor, G Czibula - Computers in Biology and Medicine, 2023 - Elsevier
Accurate in-silico identification of protein–protein interactions (PPIs) is a long-standing
problem in biology, with important implications in protein function prediction and drug …

A review of bioinformatics tools and web servers in different microarray platforms used in cancer research

RH Cathryn, SU Kumar, S Younes, H Zayed… - Advances in protein …, 2022 - Elsevier
Over the past decade, conventional lab work strategies have gradually shifted from being
limited to a laboratory setting towards a bioinformatics era to help manage and process the …

Computational Approaches to Predict Protein–Protein Interactions in Crowded Cellular Environments

G Grassmann, M Miotto, F Desantis… - Chemical …, 2024 - ACS Publications
Investigating protein–protein interactions is crucial for understanding cellular biological
processes because proteins often function within molecular complexes rather than in …

Protein-protein interaction prediction using a hybrid feature representation and a stacked generalization scheme

KH Chen, TF Wang, YJ Hu - BMC bioinformatics, 2019 - Springer
Background Although various machine learning-based predictors have been developed for
estimating protein–protein interactions, their performances vary with dataset and species …

FINDER: an automated software package to annotate eukaryotic genes from RNA-Seq data and associated protein sequences

S Banerjee, P Bhandary, M Woodhouse, TZ Sen… - BMC …, 2021 - Springer
Background Gene annotation in eukaryotes is a non-trivial task that requires meticulous
analysis of accumulated transcript data. Challenges include transcriptionally active regions …