Toward naturalistic neuroscience: Mechanisms underlying the flattening of brain hierarchy in movie-watching compared to rest and task

ML Kringelbach, YS Perl, E Tagliazucchi, G Deco - Science Advances, 2023 - science.org
Identifying the functional specialization of the brain has moved from using cognitive tasks
and resting state to using ecological relevant, naturalistic movies. We leveraged a large …

The INSIDEOUT framework provides precise signatures of the balance of intrinsic and extrinsic dynamics in brain states

G Deco, Y Sanz Perl, H Bocaccio… - Communications …, 2022 - nature.com
Finding precise signatures of different brain states is a central, unsolved question in
neuroscience. We reformulated the problem to quantify the 'inside out'balance of intrinsic …

Different hierarchical reconfigurations in the brain by psilocybin and escitalopram for depression

G Deco, Y Sanz Perl, S Johnson, N Bourke… - Nature Mental …, 2024 - nature.com
Effective interventions for neuropsychiatric disorders may work by rebalancing the brain's
functional hierarchical organization. Here we directly investigated the effects of two different …

Revisiting the global workspace orchestrating the hierarchical organization of the human brain

G Deco, D Vidaurre, ML Kringelbach - Nature human behaviour, 2021 - nature.com
A central challenge in neuroscience is how the brain organizes the information necessary to
orchestrate behaviour. Arguably, this whole-brain orchestration is carried out by a core …

Integration and segregation of large-scale brain networks during short-term task automatization

H Mohr, U Wolfensteller, RF Betzel, B Mišić… - Nature …, 2016 - nature.com
The human brain is organized into large-scale functional networks that can flexibly
reconfigure their connectivity patterns, supporting both rapid adaptive control and long-term …

The arrow of time of brain signals in cognition: Potential intriguing role of parts of the default mode network

G Deco, Y Sanz Perl, L de la Fuente, JD Sitt… - Network …, 2023 - direct.mit.edu
A promising idea in human cognitive neuroscience is that the default mode network (DMN)
is responsible for coordinating the recruitment and scheduling of networks for computing …

[HTML][HTML] Prefrontal cortex drives the flexibility of whole-brain orchestration of cognition

ML Kringelbach, G Deco - Current Opinion in Behavioral Sciences, 2024 - Elsevier
The brain is hierarchically organised across many levels, from the underlying anatomical
connectivity to the resulting functional dynamics, which supports the necessary orchestration …

[HTML][HTML] Theta-burst stimulation entrains frequency-specific oscillatory responses

EA Solomon, MR Sperling, AD Sharan, PA Wanda… - Brain stimulation, 2021 - Elsevier
Background Brain stimulation has emerged as a powerful tool in human neuroscience,
becoming integral to next-generation psychiatric and neurologic therapeutics. Theta-burst …

Neural interactions in the human frontal cortex dissociate reward and punishment learning

E Combrisson, R Basanisi, MCM Gueguen, S Rheims… - Elife, 2024 - elifesciences.org
How human prefrontal and insular regions interact while maximizing rewards and
minimizing punishments is unknown. Capitalizing on human intracranial recordings, we …