[HTML][HTML] Changes in malaria epidemiology in Africa and new challenges for elimination

IN Nkumama, WP O'meara, FHA Osier - Trends in parasitology, 2017 - cell.com
Although the burden of Plasmodium falciparum malaria is gradually declining in many parts
of Africa, it is characterized by spatial and temporal variability that presents new and …

malERA: an updated research agenda for malaria elimination and eradication

RN Rabinovich, C Drakeley, AA Djimde, BF Hall… - PLoS …, 2017 - journals.plos.org
Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …

Estimating epidemiologic dynamics from cross-sectional viral load distributions

JA Hay, L Kennedy-Shaffer, S Kanjilal, NJ Lennon… - Science, 2021 - science.org
Estimating an epidemic's trajectory is crucial for develo** public health responses to
infectious diseases, but case data used for such estimation are confounded by variable …

Multiplex assays for the identification of serological signatures of SARS-CoV-2 infection: an antibody-based diagnostic and machine learning study

J Rosado, S Pelleau, C Cockram, SH Merkling… - The Lancet …, 2021 - thelancet.com
Background Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
induces an antibody response targeting multiple antigens that changes over time. This study …

Pathogenicity and virulence of malaria: Sticky problems and tricky solutions

IS Walker, SJ Rogerson - Virulence, 2023 - Taylor & Francis
Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths
each year, concentrated in Africa and in young children, but much of the world's population …

Development and validation of serological markers for detecting recent Plasmodium vivax infection

RJ Longley, MT White, E Takashima, J Brewster… - Nature medicine, 2020 - nature.com
A major gap in the Plasmodium vivax elimination toolkit is the identification of individuals
carrying clinically silent and undetectable liver-stage parasites, called hypnozoites. This …

Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity

WJR Stone, JJ Campo, AL Ouédraogo… - Nature …, 2018 - nature.com
Infection with Plasmodium can elicit antibodies that inhibit parasite survival in the mosquito,
when they are ingested in an infectious blood meal. Here, we determine the transmission …

Current malaria infection, previous malaria exposure, and clinical profiles and outcomes of COVID-19 in a setting of high malaria transmission: an exploratory cohort …

J Achan, A Serwanga, H Wanzira, T Kyagulanyi… - The Lancet …, 2022 - thelancet.com
Background The potential effects of SARS-CoV-2 and Plasmodium falciparum co-infection
on host susceptibility and pathogenesis remain unknown. We aimed to establish the …

Integrated serologic surveillance of population immunity and disease transmission

BF Arnold, HM Scobie, JW Priest… - Emerging infectious …, 2018 - pmc.ncbi.nlm.nih.gov
Antibodies are unique among biomarkers in their ability to identify persons with protective
immunity to vaccine-preventable diseases and to measure past exposure to diverse …

THE REAL McCOIL: A method for the concurrent estimation of the complexity of infection and SNP allele frequency for malaria parasites

HH Chang, CJ Worby, A Yeka… - PLoS computational …, 2017 - journals.plos.org
As many malaria-endemic countries move towards elimination of Plasmodium falciparum,
the most virulent human malaria parasite, effective tools for monitoring malaria epidemiology …