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Nanotherapeutic approaches for transdermal drug delivery systems and their biomedical applications
Transdermal drug delivery systems (TDDS) are designed to deliver drugs through the skin
and into the systemic circulation. They offer several advantages over traditional oral or …
and into the systemic circulation. They offer several advantages over traditional oral or …
Beyond the beat: a pioneering investigation into exercise modalities for alleviating diabetic cardiomyopathy and enhancing cardiac health
Patients with preexisting cardiovascular disease or those at high risk for develo** the
condition are often offered exercise as a form of therapy. Patients with cancer who are at an …
condition are often offered exercise as a form of therapy. Patients with cancer who are at an …
Hypoxia-driven protease legumain promotes immunosuppression in glioblastoma
Glioblastoma (GBM) is a hypoxic and" immune-cold" tumor containing rich stromal signaling
molecules and cell populations, such as proteases and immunosuppressive tumor …
molecules and cell populations, such as proteases and immunosuppressive tumor …
Triple coumarin-based 5-fluorouracil prodrugs, their synthesis, characterization, and release kinetics
YF Mustafa - Journal of Molecular Structure, 2024 - Elsevier
Fluorouracil (5-FU) has been commonly used as a chemotherapy medication in cancer
management. However, owing to its substantial side effects, limited selectivity, and tumor …
management. However, owing to its substantial side effects, limited selectivity, and tumor …
[HTML][HTML] Data-independent acquisition mass spectrometry analysis of FFPE rectal cancer samples offers in-depth proteomics characterization of the response to …
A Stanojevic, M Samiotaki, V Lygirou… - International Journal of …, 2023 - mdpi.com
Locally advanced rectal cancer (LARC) presents a challenge in identifying molecular
markers linked to the response to neoadjuvant chemoradiotherapy (nCRT). This study …
markers linked to the response to neoadjuvant chemoradiotherapy (nCRT). This study …
Comprehensive overview of utilizing metal-organic frameworks (MOFs) for precise cancer drug delivery
Cancer is a complex disease that develops due to complex interactions between hereditary
and environmental variables. This devastating disease has far-reaching consequences for …
and environmental variables. This devastating disease has far-reaching consequences for …
Cardiomegaly: Navigating the uncharted territories of heart failure-A multimodal radiological journey through advanced imaging, pathophysiological landscapes, and …
Cardiomegaly is among the disorders categorized by a structural enlargement of the heart
by any of the situations including pregnancy, resulting in damage to heart muscles and …
by any of the situations including pregnancy, resulting in damage to heart muscles and …
[HTML][HTML] Cancer cell secreted legumain promotes gastric cancer resistance to anti-PD-1 immunotherapy by enhancing macrophage M2 polarization
X Pei, SL Zhang, BQ Qiu, PF Zhang, TS Liu, Y Wang - Pharmaceuticals, 2024 - mdpi.com
The interaction between cancer cells and immune cells plays critical roles in gastric cancer
(GC) progression and immune evasion. Forced legumain (LGMN) is one of the …
(GC) progression and immune evasion. Forced legumain (LGMN) is one of the …
Heartfelt living: Deciphering the link between lifestyle choices and cardiovascular vitality
Cardiovascular diseases (CVDs) are still leading to a significant number of deaths
worldwide despite the remarkable advancements in medical technology and pharmacology …
worldwide despite the remarkable advancements in medical technology and pharmacology …
Assessment of circulating proteins in thyroid cancer: Proteome-wide Mendelian randomization and colocalization analysis
Q Fan, S Wen, Y Zhang, X Feng, W Zheng, X Liang… - Iscience, 2024 - cell.com
The causality between circulating proteins and thyroid cancer (TC) remains unclear. We
employed five large-scale circulating proteomic genome-wide association studies (GWASs) …
employed five large-scale circulating proteomic genome-wide association studies (GWASs) …