Design of therapeutic biomaterials to control inflammation
Z Tu, Y Zhong, H Hu, D Shao, R Haag… - Nature Reviews …, 2022 - nature.com
Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …
The tumor EPR effect for cancer drug delivery: Current status, limitations, and alternatives
Over the past three decades, the enhanced permeability and retention (EPR) effect has
been considered the basis of tumor-targeted drug delivery. Various cancer nanomedicines …
been considered the basis of tumor-targeted drug delivery. Various cancer nanomedicines …
Chemical and biophysical signatures of the protein corona in nanomedicine
An inconvenient hurdle in the practice of nanomedicine is the protein corona, a spontaneous
collection of biomolecular species by nanoparticles in living systems. The protein corona is …
collection of biomolecular species by nanoparticles in living systems. The protein corona is …
The use of alternative strategies for enhanced nanoparticle delivery to solid tumors
M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …
decade. Classically, scientists have tried to improve NM delivery by employing passive or …
The ancillary effects of nanoparticles and their implications for nanomedicine
Nanoparticles are often engineered as a scaffolding system to combine targeting, imaging
and/or therapeutic moieties into a unitary agent. However, mostly overlooked, the …
and/or therapeutic moieties into a unitary agent. However, mostly overlooked, the …
Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches
Skin cancer is a global threat to the healthcare system and is estimated to incline
tremendously in the next 20 years, if not diagnosed at an early stage. Even though it is …
tremendously in the next 20 years, if not diagnosed at an early stage. Even though it is …
Advances in nanomaterial-mediated photothermal cancer therapies: toward clinical applications
Photothermal therapy (PTT) has attracted extensive research attention as a noninvasive and
selective treatment strategy for numerous cancers. PTT functions via photothermal effects …
selective treatment strategy for numerous cancers. PTT functions via photothermal effects …
Engineering tumoral vascular leakiness with gold nanoparticles
Delivering cancer therapeutics to tumors necessitates their escape from the surrounding
blood vessels. Tumor vasculatures are not always sufficiently leaky. Herein, we engineer …
blood vessels. Tumor vasculatures are not always sufficiently leaky. Herein, we engineer …
Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer
The nonradiative conversion of light energy into heat (photothermal therapy, PTT) or sound
energy (photoacoustic imaging, PAI) has been intensively investigated for the treatment and …
energy (photoacoustic imaging, PAI) has been intensively investigated for the treatment and …
Noncancerous disease-targeting AIEgens
Y Duo, G Luo, W Zhang, R Wang, GG **ao… - Chemical Society …, 2023 - pubs.rsc.org
Noncancerous diseases include a wide plethora of medical conditions beyond cancer and
are a major cause of mortality around the world. Despite progresses in clinical research …
are a major cause of mortality around the world. Despite progresses in clinical research …