[HTML][HTML] Optical imaging and spectroscopy for the study of the human brain: status report

H Ayaz, WB Baker, G Blaney, DA Boas… - …, 2022‏ - spiedigitallibrary.org
This report is the second part of a comprehensive two-part series aimed at reviewing an
extensive and diverse toolkit of novel methods to explore brain health and function. While …

Small vessels are a big problem in neurodegeneration and neuroprotection

ŞE Erdener, T Dalkara - Frontiers in neurology, 2019‏ - frontiersin.org
The cerebral microcirculation holds a critical position to match the high metabolic demand
by neuronal activity. Functionally, microcirculation is virtually inseparable from other nervous …

Dynamic light scattering imaging

DD Postnov, J Tang, SE Erdener, K Kılıç, DA Boas - Science advances, 2020‏ - science.org
We introduce dynamic light scattering imaging (DLSI) to enable the wide-field measurement
of the speckle temporal intensity autocorrelation function. DLSI uses the full temporal …

Shear-induced diffusion in dense granular fluids

P Rognon, M Macaulay - Soft matter, 2021‏ - pubs.rsc.org
Granular materials are comprised of solid, athermal grains. Whilst immune to thermal
motion, these grains move and diffuse when they undergo shear deformation. Here we …

Choosing a model for laser speckle contrast imaging

C Liu, K Kılıç, SE Erdener, DA Boas… - Biomedical Optics …, 2021‏ - opg.optica.org
Laser speckle contrast imaging (LSCI) is a real-time full-field non-invasive technique, which
is broadly applied to visualize blood flow in biomedical applications. In its foundation is the …

Time-of-flight resolved light field fluctuations reveal deep human tissue physiology

O Kholiqov, W Zhou, T Zhang, VN Du Le… - Nature …, 2020‏ - nature.com
Red blood cells (RBCs) transport oxygen to tissues and remove carbon dioxide. Diffuse
optical flowmetry (DOF) assesses deep tissue RBC dynamics by measuring coherent …

Cortical microvascular blood flow velocity map** by combining dynamic light scattering optical coherence tomography and two-photon microscopy

Q Pian, M Alfadhel, J Tang, GV Lee, B Li… - Journal of …, 2023‏ - spiedigitallibrary.org
Significance The accurate large-scale map** of cerebral microvascular blood flow velocity
is crucial for a better understanding of cerebral blood flow (CBF) regulation. Although optical …

[HTML][HTML] Diffuse optical monitoring of cerebral hemodynamics and oxygen metabolism during and after cardiopulmonary bypass: hematocrit correction and …

EJ Benson, DI Aronowitz, RM Forti, A Lafontant… - Metabolites, 2023‏ - mdpi.com
Cardiopulmonary bypass (CPB) provides cerebral oxygenation and blood flow (CBF) during
neonatal congenital heart surgery, but the impacts of CPB on brain oxygen supply and …

Functional ultrasound speckle decorrelation‐based velocimetry of the brain

J Tang, DD Postnov, K Kilic, SE Erdener… - Advanced …, 2020‏ - Wiley Online Library
A high‐speed, contrast‐free, quantitative ultrasound velocimetry (vUS) for blood flow velocity
imaging throughout the rodent brain is developed based on the normalized first‐order …

Measuring neuronal activity with diffuse correlation spectroscopy: a theoretical investigation

X Cheng, EJ Sie, S Naufel, DA Boas… - …, 2021‏ - spiedigitallibrary.org
Significance: Diffuse correlation spectroscopy (DCS) measures cerebral blood flow non-
invasively. Variations in blood flow can be used to detect neuronal activities, but its peak has …