[HTML][HTML] An overview of substrate stiffness guided cellular response and its applications in tissue regeneration

B Yi, Q Xu, W Liu - Bioactive materials, 2022 - Elsevier
Cell-matrix interactions play a critical role in tissue repair and regeneration. With gradual
uncovering of substrate mechanical characteristics that can affect cell-matrix interactions …

Local force and geometry sensing regulate cell functions

V Vogel, M Sheetz - Nature reviews Molecular cell biology, 2006 - nature.com
The shapes of eukaryotic cells and ultimately the organisms that they form are defined by
cycles of mechanosensing, mechanotransduction and mechanoresponse. Local sensing of …

Emerging diversity in lipid–protein interactions

V Corradi, BI Sejdiu, H Mesa-Galloso… - Chemical …, 2019 - ACS Publications
Membrane lipids interact with proteins in a variety of ways, ranging from providing a stable
membrane environment for proteins to being embedded in to detailed roles in complicated …

Water in nanopores and biological channels: a molecular simulation perspective

CI Lynch, S Rao, MSP Sansom - Chemical reviews, 2020 - ACS Publications
This Review explores the dynamic behavior of water within nanopores and biological
channels in lipid bilayer membranes. We focus on molecular simulation studies, alongside …

Designing carbon nanotube membranes for efficient water desalination

B Corry - The Journal of Physical Chemistry B, 2008 - ACS Publications
The transport of water and ions through membranes formed from carbon nanotubes ranging
in diameter from 6 to 11 Å is studied using molecular dynamics simulations under …

Multiscale simulations of biological membranes: the challenge to understand biological phenomena in a living substance

G Enkavi, M Javanainen, W Kulig, T Róg… - Chemical …, 2019 - ACS Publications
Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

Accelerating molecular modeling applications with graphics processors

JE Stone, JC Phillips, PL Freddolino… - Journal of …, 2007 - Wiley Online Library
Molecular mechanics simulations offer a computational approach to study the behavior of
biomolecules at atomic detail, but such simulations are limited in size and timescale by the …

Imaging α-hemolysin with molecular dynamics: ionic conductance, osmotic permeability, and the electrostatic potential map

A Aksimentiev, K Schulten - Biophysical journal, 2005 - cell.com
Abstract α-Hemolysin of Staphylococcus aureus is a self-assembling toxin that forms a water-
filled transmembrane channel upon oligomerization in a lipid membrane. Apart from being …

Water in nonpolar confinement: from nanotubes to proteins and beyond

JC Rasaiah, S Garde, G Hummer - Annu. Rev. Phys. Chem., 2008 - annualreviews.org
Water molecules confined to nonpolar pores and cavities of nanoscopic dimensions exhibit
highly unusual properties. Water filling is strongly cooperative, with the possible coexistence …

Mechanosensitive channels: what can they do and how do they do it?

ES Haswell, R Phillips, DC Rees - Structure, 2011 - cell.com
While mechanobiological processes employ diverse mechanisms, at their heart are force-
induced perturbations in the structure and dynamics of molecules capable of triggering …