The immunology of hepatocellular carcinoma
M Ringelhan, D Pfister, T O'Connor, E Pikarsky… - Nature …, 2018 - nature.com
In contrast to most other malignancies, hepatocellular carcinoma (HCC), which accounts for
approximately 90% of primary liver cancers, arises almost exclusively in the setting of …
approximately 90% of primary liver cancers, arises almost exclusively in the setting of …
Advances in the role of STAT3 in macrophage polarization
T **a, M Zhang, W Lei, R Yang, S Fu, Z Fan… - Frontiers in …, 2023 - frontiersin.org
The physiological processes of cell growth, proliferation, differentiation, and apoptosis are
closely related to STAT3, and it has been demonstrated that aberrant STAT3 expression has …
closely related to STAT3, and it has been demonstrated that aberrant STAT3 expression has …
Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors
Signal transducers and activators of transcription (STATs) comprise a family of cytoplasmic
transcription factors that mediate intracellular signaling that is usually generated at cell …
transcription factors that mediate intracellular signaling that is usually generated at cell …
Signal transducer and activator of transcription (STATs) proteins in cancer and inflammation: functions and therapeutic implication
Signal Transducer and Activator of Transcription (STAT) pathway is connected upstream
with Janus kinases (JAK) family protein and capable of integrating inputs from different …
with Janus kinases (JAK) family protein and capable of integrating inputs from different …
Noncoding RNAs as regulators of STAT3 pathway in gastrointestinal cancers: Roles in cancer progression and therapeutic response
M Ashrafizadeh, CD Mohan… - Medicinal research …, 2023 - Wiley Online Library
Gastrointestinal (GI) tumors (cancers of the esophagus, gastric, liver, pancreas, colon, and
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …
Non-coding RNA in hepatocellular carcinoma: mechanisms, biomarkers and therapeutic targets
The majority of the human genome is not translated into proteins but can be transcribed into
RNA. Even though the resulting non-coding RNAs (ncRNAs) do not encode for proteins …
RNA. Even though the resulting non-coding RNAs (ncRNAs) do not encode for proteins …
Sesame inhibits cell proliferation and induces apoptosis through inhibition of STAT-3 translocation in thyroid cancer cell lines (FTC-133)
Y Ma, T Karunakaran, VP Veeraraghavan… - Biotechnology and …, 2019 - Springer
Thyroid cancer is the most widespread endocrine malignant cancer and its worldwide
occurrence rates are swiftly mounting more pressure in the research institutions. Even …
occurrence rates are swiftly mounting more pressure in the research institutions. Even …
The multifaceted role of curcumin in cancer prevention and treatment
Despite significant advances in treatment modalities over the last decade, neither the
incidence of the disease nor the mortality due to cancer has altered in the last thirty years …
incidence of the disease nor the mortality due to cancer has altered in the last thirty years …
Role of nonresolving inflammation in hepatocellular carcinoma development and progression
LX Yu, Y Ling, HY Wang - NPJ precision oncology, 2018 - nature.com
Hepatocellular carcinoma (HCC) has become a leading cause of cancer-related death,
making the elucidation of its underlying mechanisms an urgent priority. Inflammation is an …
making the elucidation of its underlying mechanisms an urgent priority. Inflammation is an …
An update on pharmacological potential of boswellic acids against chronic diseases
Natural compounds, in recent years, have attracted significant attention for their use in the
prevention and treatment of diverse chronic diseases as they are devoid of major toxicities …
prevention and treatment of diverse chronic diseases as they are devoid of major toxicities …