Background Decidualization of the human endometrium, which involves a dramatic
morphological and functional differentiation of human endometrial stromal cells (ESC s), is …

Vascular endothelial growth factor (VEGF) is a well-known angiogenic factor that plays a
critical role in various physiological and pathological processes. VEGF also contributes to …

Background Repair deficiency after endometrial injury is an important reason for intra-
uterine adhesions, amenorrhea, and infertility in females. Bone marrow-derived …

Successful implantation requires synchronous development of embryo and endometrium.
Endometrial receptivity results from progesterone‐induced differentiation of endometrial …

Embryonic diapause–a period of embryonic suspension at the blastocyst stage–is a
fascinating phenomenon that occurs in over 130 species of mammals, ranging from bears …

The mammalian blastocyst exhibits a high capacity for aerobic glycolysis, a metabolic
characteristic of tumours. It has been considered that aerobic glycolysis is a means to …

The success of clinical IVF was initially compromised by sub-optimal culture conditions,
resulting in impaired embryo development (1–6) and a subsequent loss of viability …

Preeclampsia (PE) is a leading cause of maternal and neonatal mortality and morbidity
worldwide, impacting the long‐term health of both mother and offspring. PE has long been …

Pregnancy is established during the periconceptional period as a continuum beginning with
blastocyst attachment to the endometrial epithelial surface followed by embryo invasion and …

Embryo implantation into maternal endometrium is critical for initiation and establishment of
pregnancy, requiring developmental synchrony between endometrium and blastocyst …