OBJECTIVE: This overview focuses on neurobiological abnormalities found in subjects with
schizotypal personality disorder, the prototype of the schizophrenia spectrum disorders, and …

The study of schizotypal personality disorder (SPD) is important clinically, as it is
understudied, challenging to treat, often under-recognized or misdiagnosed, and associated …

BACKGROUND: Given the wealth of data in the literature on schizophrenia
endophenotypes, it is useful to have one source to reference their frequency data. We …

We investigated whether variation in auditory experience in humans during development
alters the macroscopic neuroanatomy of primary or auditory association cortices. Volumetric …

Schizophrenia is a worldwide, prevalent disorder with a multifactorial but highly genetic
aetiology. A constant prevalence rate in the face of reduced fecundity has caused some to …

BACKGROUND: Evidence is accumulating that suggests borderline personality disorder
(BPD) and posttraumatic stress disorder (PTSD) are related to small hippocampal size …

Common abnormalities within the schizophrenia spectrum may be essential for the
pathogenesis of schizophrenia, but additional pathological changes may be required for the …

Changes in hemispheric asymmetry and inter-hemispheric connectivity have been reported
in schizophrenia. However, the genetic contribution to these alterations is still unclear. In the …

Human beings are social organisms with an intrinsic desire to seek and participate in social
interactions. Social anhedonia is a personality trait characterized by a reduced desire for …

Magnetic resonance imaging (MRI) studies have revealed fronto-temporal cortical gray
matter volume reductions in schizophrenia. However, to date studies have not examined …