AI-powered microfluidics: sha** the future of phenotypic drug discovery
J Liu, H Du, L Huang, W **e, K Liu… - … Applied Materials & …, 2024 - ACS Publications
Phenotypic drug discovery (PDD), which involves harnessing biological systems directly to
uncover effective drugs, has undergone a resurgence in recent years. The rapid …
uncover effective drugs, has undergone a resurgence in recent years. The rapid …
Imaging technologies for microfluidic biochips
With the growing interest in biochips, numerous efforts have been made to recapitulate a
more reliable and physiologically relevant environment within chips, resulting in significant …
more reliable and physiologically relevant environment within chips, resulting in significant …
Trends in hyperspectral imaging: from environmental and health sensing to structure-property and nano-bio interaction studies
EM Rodrigues, E Hemmer - Analytical and Bioanalytical Chemistry, 2022 - Springer
Hyperspectral imaging (HSI) is a technique that allows for the simultaneous acquisition of
both spatial and spectral information. While HSI has been known for years in the field of …
both spatial and spectral information. While HSI has been known for years in the field of …
Technological advances in tumor-on-chip technology: From bench to bedside
Simple Summary Various 3D in vitro tumor models are rapidly advancing cancer research.
Unlike animal models, they can be produced quickly and are amenable to high-throughput …
Unlike animal models, they can be produced quickly and are amenable to high-throughput …
Advanced devices for tumor diagnosis and therapy
At present, tumor diagnosis is performed using common procedures, which are slow, costly,
and still presenting difficulties in diagnosing tumors at their early stage. Tumor therapeutic …
and still presenting difficulties in diagnosing tumors at their early stage. Tumor therapeutic …
Carboplatin sensitivity in epithelial ovarian cancer cell lines: The impact of model systems
Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy in North America,
underscoring the need for the development of new therapeutic strategies for the …
underscoring the need for the development of new therapeutic strategies for the …
Live-cell fluorescence spectral imaging as a data science challenge
JP Acuña-Rodriguez, JP Mena-Vega… - Biophysical …, 2022 - Springer
Live-cell fluorescence spectral imaging is an evolving modality of microscopy that uses
specific properties of fluorophores, such as excitation or emission spectra, to detect multiple …
specific properties of fluorophores, such as excitation or emission spectra, to detect multiple …
Microfluidic Techniques for Next‐Generation Organoid Systems
J Gong, M Li, J Kang, Z Yin, Z Cha… - Advanced Materials …, 2022 - Wiley Online Library
Organoids are 3D multicellular structures derived from pluripotent stem cells (PSCs) or adult
stem cells (ASCs), which have attracted increasing interest in the fields of drug screening …
stem cells (ASCs), which have attracted increasing interest in the fields of drug screening …
Analysis of cellular response to drugs with a microfluidic single-cell platform based on hyperspectral imaging
L Liu, L Zhang, X Zhang, X Dong, X Jiang, X Huang… - Analytica Chimica …, 2024 - Elsevier
Background Cellular response to pharmacological action of drugs is significant for drug
development. Traditional detection method for cellular response to drugs normally rely on …
development. Traditional detection method for cellular response to drugs normally rely on …
Radiotherapy on-chip: microfluidics for translational radiation oncology
The clinical importance of radiotherapy in the treatment of cancer patients justifies the
development and use of research tools at the fundamental, pre-clinical, and ultimately …
development and use of research tools at the fundamental, pre-clinical, and ultimately …