Tumor necrosis factor (TNF) is one of the main cytokines regulating a pro-inflammatory
environment. It has been related to several cell functions, for instance, phagocytosis …

Self-assembling peptides are a type of biomaterial rapidly emerging in the fields of
biomedicine and material sciences due to their promise in biocompatibility and effectiveness …

Several studies have shown that epitope vaccines exhibit substantial advantages over
conventional vaccines. However, epitope vaccines are associated with limited immunity …

Active immunotherapies raising antibody responses against autologous targets are
receiving increasing interest as alternatives to the administration of manufactured …

Rheumatoid arthritis (RA) is a joint-related autoimmune disease that is difficult to cure. Most
therapeutics act to alleviate the symptoms but not correct the causes of RA. Novel strategies …

The study of peptides (synthetic or corresponding to discrete regions of proteins) has
facilitated the understanding of protein structure–activity relationships. Short peptides can …

The burden of atherosclerotic cardiovascular disease contributes to a large proportion of
morbidity and mortality, globally. Vaccination against atherosclerosis has been proposed for …

Drug development targeting the most frequently mutation G12D of KRAS has great
significance. As an attractive immunotherapy, cancer vaccines can overcome binding …

Recently, several novel medications, such as Ustekinumab, Infliximab, and Vedolizumab,
have emerged as potential options for inflammatory bowel disease (IBD) management …

Tumor neoantigens are ideal targets for cancer immunotherapy as they are recognized by
host immune system as foreigners and can elicit tumor-specific immune responses …