Imidazolium salts, distinct from their parent imidazoles, are made up of a discrete cation and
anion pair, and have found widespread utility as ionic liquids. A lesser known function of …

Background: The imidazole nucleus is inimitable and ubiquitous and it is very well known to
play an important role in living organisms. Imidazole derivatives are under intensive …

A series of novel hybrid compounds between 2-phenylbenzofuran and imidazole have been
prepared and evaluated in vitro against a panel of human tumor cell lines. The results …

Novel functionalized 2-phenylindole derivatives, their derived imidazolethione and 1, 2, 4-
triazinethione were synthesized. The bicyclic compounds thiazoloimidazole and …

A new molecular modelling approach based on physico-chemical and pharmacokinetic
properties, called Volsurf plus, was used to design new heterocyclic compounds with …

A set of styryl-and bis-styryl dyes, varying in length, aromatic surface, net positive charge
and steric positioning or bulkiness of substituents, was tested for interactions with various ds …

Almond and VolSurf+ modelling procedures allowed the structural design of new di-and
mono-heteroaryl-ethylenes. The structural modifications suggested by the molecular …

A series of novel hybrid compounds of 2-phenyl-3-alkylbenzofuran and imidazole or triazole
were prepared and evaluated in vitro against a panel of human tumor cell lines. The results …

A series of novel 2-substituted indoline imidazolium salt derivatives has been prepared and
evaluated in vitro against a panel of human tumor cell lines. The results suggest that the …

Background: Breast cancer is one of the leading types of cancer in women worldwide.
Quantitative structure–activity relationship (QSAR) methods play an important role in the …