Next-generation sequencing: insights to advance clinical investigations of the microbiome
Next-generation sequencing (NGS) technology has advanced our understanding of the
human microbiome by allowing for the discovery and characterization of unculturable …
human microbiome by allowing for the discovery and characterization of unculturable …
Environmental DNA metabarcoding: Transforming how we survey animal and plant communities
The genomic revolution has fundamentally changed how we survey biodiversity on earth.
High‐throughput sequencing (“HTS”) platforms now enable the rapid sequencing of DNA …
High‐throughput sequencing (“HTS”) platforms now enable the rapid sequencing of DNA …
Reduction of microbial diversity in grassland soil is driven by long-term climate warming
Anthropogenic climate change threatens ecosystem functioning. Soil biodiversity is essential
for maintaining the health of terrestrial systems, but how climate change affects the richness …
for maintaining the health of terrestrial systems, but how climate change affects the richness …
Kraken: ultrafast metagenomic sequence classification using exact alignments
Kraken is an ultrafast and highly accurate program for assigning taxonomic labels to
metagenomic DNA sequences. Previous programs designed for this task have been …
metagenomic DNA sequences. Previous programs designed for this task have been …
[PDF][PDF] MicrobiomeAnalyst: a web-based tool for comprehensive statistical, visual and meta-analysis of microbiome data
The widespread application of next-generation sequencing technologies has revolutionized
microbiome research by enabling high-throughput profiling of the genetic contents of …
microbiome research by enabling high-throughput profiling of the genetic contents of …
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight
INTRODUCTION To date, 559 humans have been flown into space, but long-duration (> 300
days) missions are rare (n= 8 total). Long-duration missions that will take humans to Mars …
days) missions are rare (n= 8 total). Long-duration missions that will take humans to Mars …
Gut microbiota dysbiosis contributes to the development of hypertension
Background Recently, the potential role of gut microbiome in metabolic diseases has been
revealed, especially in cardiovascular diseases. Hypertension is one of the most prevalent …
revealed, especially in cardiovascular diseases. Hypertension is one of the most prevalent …
MEGAN community edition-interactive exploration and analysis of large-scale microbiome sequencing data
There is increasing interest in employing shotgun sequencing, rather than amplicon
sequencing, to analyze microbiome samples. Typical projects may involve hundreds of …
sequencing, to analyze microbiome samples. Typical projects may involve hundreds of …
Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome
Microorganisms living inside plants can promote plant growth and health, but their genomic
and functional diversity remain largely elusive. Here, metagenomics and network inference …
and functional diversity remain largely elusive. Here, metagenomics and network inference …
A human gut microbial gene catalogue established by metagenomic sequencing
To understand the impact of gut microbes on human health and well-being it is crucial to
assess their genetic potential. Here we describe the Illumina-based metagenomic …
assess their genetic potential. Here we describe the Illumina-based metagenomic …