Glycomimetics for the inhibition and modulation of lectins

S Leusmann, P Ménová, E Shanin, A Titz… - Chemical Society …, 2023 - pubs.rsc.org
Carbohydrates are essential mediators of many processes in health and disease. They
regulate self-/non-self-discrimination, are key elements of cellular communication, cancer …

Plant–microbe interactions in the apoplast: Communication at the plant cell wall

S Dora, OM Terrett, C Sánchez-Rodríguez - The Plant Cell, 2022 - academic.oup.com
The apoplast is a continuous plant compartment that connects cells between tissues and
organs and is one of the first sites of interaction between plants and microbes. The plant cell …

gmx_MMPBSA: a new tool to perform end-state free energy calculations with GROMACS

MS Valdés-Tresanco… - Journal of chemical …, 2021 - ACS Publications
Molecular mechanics/Poisson–Boltzmann (Generalized-Born) surface area is one of the
most popular methods to estimate binding free energies. This method has been proven to …

Lectin microarrays: concept, principle and applications

J Hirabayashi, M Yamada, A Kuno… - Chemical Society …, 2013 - pubs.rsc.org
The lectin microarray is a novel platform for glycan analysis, having emerged only in recent
years. Unlike other conventional methods, eg, liquid chromatography and mass …

Exploring the diverse biological significance and roles of fucosylated oligosaccharides

B Pekdemir, S Karav - Frontiers in Molecular Biosciences, 2024 - frontiersin.org
Long since, carbohydrates were thought to be used just as an energy source and structural
material. However, in recent years, with the emergence of the field of glycobiology and …

Mushroom lectins: specificity, structure and bioactivity relevant to human disease

MAA Hassan, R Rouf, E Tiralongo, TW May… - International journal of …, 2015 - mdpi.com
Lectins are non-immunoglobulin proteins that bind diverse sugar structures with a high
degree of selectivity. Lectins play crucial role in various biological processes such as …

[PDF][PDF] On the life of Ralstonia solanacearum, a destructive bacterial plant pathogen

B Álvarez, EG Biosca, MM López - Current research, technology …, 2010 - researchgate.net
Ralstonia solanacearum is a relevant and widespread phytopathogenic bacterium that
causes a wilt disease with deadly effects on many economically important crops and …

Integrated regulation of the type III secretion system and other virulence determinants in Ralstonia solanacearum

M Valls, S Genin, C Boucher - PLoS pathogens, 2006 - journals.plos.org
In many plant and animal bacterial pathogens, the Type III secretion system (TTSS) that
directly translocates effector proteins into the eukaryotic host cells is essential for the …

Binding sugars: from natural lectins to synthetic receptors and engineered neolectins

J Arnaud, A Audfray, A Imberty - Chemical Society Reviews, 2013 - pubs.rsc.org
The large diversity and complexity of glycan structures together with their crucial role in
many biological or pathological processes require the development of new high-throughput …

Isothermal titration calorimetry: general formalism using binding polynomials

E Freire, A Schön, A Velazquez‐Campoy - Methods in enzymology, 2009 - Elsevier
The theory of the binding polynomial constitutes a very powerful formalism by which many
experimental biological systems involving ligand binding can be analyzed under a unified …