Estrogens and androgens in skeletal physiology and pathophysiology
Estrogens and androgens influence the growth and maintenance of the mammalian
skeleton and are responsible for its sexual dimorphism. Estrogen deficiency at menopause …
skeleton and are responsible for its sexual dimorphism. Estrogen deficiency at menopause …
Metabolic benefits afforded by estradiol and testosterone in both sexes: clinical considerations
Testosterone (T) and 17β-estradiol (E2) are produced in male and female humans and are
potent metabolic regulators in both sexes. When E2 and T production stops or decreases …
potent metabolic regulators in both sexes. When E2 and T production stops or decreases …
International Society for the Study of Women's Sexual Health clinical practice guideline for the use of systemic testosterone for hypoactive sexual desire disorder in …
ABSTRACT Background The Global Consensus Position Statement on the Use of
Testosterone Therapy for Women (Global Position Statement) recommended testosterone …
Testosterone Therapy for Women (Global Position Statement) recommended testosterone …
Safety and efficacy of testosterone for women: a systematic review and meta-analysis of randomised controlled trial data
Background The benefits and risks of testosterone treatment for women with diminished
sexual wellbeing remain controversial. We did a systematic review and meta-analysis to …
sexual wellbeing remain controversial. We did a systematic review and meta-analysis to …
Androgen therapy in women: a reappraisal: an Endocrine Society clinical practice guideline
Objective: To update practice guidelines for the therapeutic use of androgens in women.
Participants: A Task Force appointed by the Endocrine Society, American Congress of …
Participants: A Task Force appointed by the Endocrine Society, American Congress of …
Invited review: aging and sarcopenia
TJ Doherty - Journal of applied physiology, 2003 - journals.physiology.org
Aging is associated with progressive loss of neuromuscular function that often leads to
progressive disability and loss of independence. The term sarcopenia is now commonly …
progressive disability and loss of independence. The term sarcopenia is now commonly …
Testosterone in women—the clinical significance
SR Davis, S Wahlin-Jacobsen - The lancet Diabetes & …, 2015 - thelancet.com
Testosterone is an essential hormone for women, with physiological actions mediated
directly or via aromatisation to oestradiol throughout the body. Despite the crucial role of …
directly or via aromatisation to oestradiol throughout the body. Despite the crucial role of …
Is there a gender difference in strength of sex drive? Theoretical views, conceptual distinctions, and a review of relevant evidence
RF Baumeister, KR Catanese… - Personality and social …, 2001 - journals.sagepub.com
The sex drive refers to the strength of sexual motivation. Across many different studies and
measures, men have been shown to have more frequent and more intense sexual desires …
measures, men have been shown to have more frequent and more intense sexual desires …
Onset of the menopause transition: the earliest signs and symptoms
CR Gracia, EW Freeman - Obstetrics and Gynecology Clinics, 2018 - obgyn.theclinics.com
Four of 5 women experience psychological or physical symptoms around menopause, with
varying degrees of severity and disruption in their lives. 1 Clinicians and women normally …
varying degrees of severity and disruption in their lives. 1 Clinicians and women normally …
Generation and characterization of androgen receptor knockout (ARKO) mice: An in vivo model for the study of androgen functions in selective tissues
S Yeh, MY Tsai, Q Xu, XM Mu… - Proceedings of the …, 2002 - National Acad Sciences
By using a cre-lox conditional knockout strategy, we report here the generation of androgen
receptor knockout (ARKO) mice. Phenotype analysis shows that ARKO male mice have a …
receptor knockout (ARKO) mice. Phenotype analysis shows that ARKO male mice have a …