Defective viral genomes are key drivers of the virus–host interaction

M Vignuzzi, CB López - Nature microbiology, 2019 - nature.com
Viruses survive often harsh host environments, yet we know little about the strategies they
utilize to adapt and subsist given their limited genomic resources. We are beginning to …

[HTML][HTML] Towards understanding KSHV fusion and entry

SJ Dollery - Viruses, 2019 - mdpi.com
How viruses enter cells is of critical importance to pathogenesis in the host and for treatment
strategies. Over the last several years, the herpesvirus field has made numerous and …

Structures of Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus virions reveal species-specific tegument and envelope features

J Zhen, J Chen, H Huang, S Liao, S Liu, Y Yuan… - Journal of …, 2024 - journals.asm.org
Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV) are
classified into the gammaherpesvirus subfamily of Herpesviridae, which stands out from its …

Kaposi's sarcoma-associated herpesvirus immediate early proteins trigger FOXQ1 expression in oral epithelial cells, engaging in a novel lytic cycle-sustaining positive …

N Atyeo, MY Chae, Z Toth, A Sharma… - Journal of Virology, 2023 - journals.asm.org
Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic gammaherpesvirus that
can replicate in oral epithelial cells to promote viral transmission via saliva. To identify novel …

DNA-packing portal and capsid-associated tegument complexes in the tumor herpesvirus KSHV

D Gong, X Dai, J Jih, YT Liu, GQ Bi, R Sun, ZH Zhou - Cell, 2019 - cell.com
Assembly of Kaposi's sarcoma-associated herpesvirus (KSHV) begins at a bacteriophage-
like portal complex that nucleates formation of an icosahedral capsid with capsid-associated …

[HTML][HTML] The ORF45 protein of kaposi's sarcoma-associated herpesvirus and its critical role in the viral life cycle

N Atyeo, B Papp - Viruses, 2022 - mdpi.com
Kaposi's sarcoma-associated herpesvirus (KSHV) protein ORF45 is a virion-associated
tegument protein that is unique to the gammaherpesvirus family. Generation of KSHV …

Kaposi sarcoma-associated herpesvirus complement control protein (KCP) and glycoprotein K8.1 are not required for viral infection in vitro or in vivo

M Muniraju, LZ Mutsvunguma, IG Reidel… - Journal of …, 2024 - journals.asm.org
Kaposi sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus-8, is the
causal agent of Kaposi sarcoma, a cancer that appears as tumors on the skin or mucosal …

Compartmented neuronal cultures reveal two distinct mechanisms for alpha herpesvirus escape from genome silencing

OO Koyuncu, MA MacGibeny, IB Hogue… - PLoS …, 2017 - journals.plos.org
Alpha herpesvirus genomes encode the capacity to establish quiescent infections (ie
latency) in the peripheral nervous system for the life of their hosts. Multiple times during …

Structures of capsid and capsid-associated tegument complex inside the Epstein–Barr virus

W Liu, Y Cui, C Wang, Z Li, D Gong, X Dai, GQ Bi… - Nature …, 2020 - nature.com
As the first discovered human cancer virus, Epstein–Barr virus (EBV) causes Burkitt's
lymphoma and nasopharyngeal carcinoma. Isolating virions for determining high-resolution …

Cellular receptors involved in KSHV infection

E van der Meulen, M Anderton, MJ Blumenthal… - Viruses, 2021 - mdpi.com
The process of Kaposi's Sarcoma Herpes Virus'(KSHV) entry into target cells is complex and
engages several viral glycoproteins which bind to a large range of host cell surface …