Invasive fungal infections pose an important threat to public health and are an under-
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …

The fungal cell wall is essential for growth and survival, and is a key target for antifungal
drugs and the immune system. The cell wall must be robust but flexible, protective and …

Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …

The extracellular matrix is a critical component of microbial biofilms, such as dental plaque,
maintaining the spatial arrangement of cells and coordinating cellular functions throughout …

Pathogenic microorganisms and their chronic pathogenicity are significant concerns in
biomedical research. Biofilm-linked persistent infections are not easy to treat due to resident …

SUMMARY A significant increase in the incidence of Candida-mediated infections has been
observed in the last decade, mainly due to rising numbers of susceptible individuals …

Candida albicans is a common fungus of the human microbiota. While generally a harmless
commensal in healthy individuals, several factors can lead to its overgrowth and cause a …

Human fungal infections are a historically neglected area of disease research, yet they
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …

The host type I interferon (IFN) pathway is a major signature of inflammation induced by the
human fungal pathogen, Candida albicans. However, the molecular mechanism for …

Bacterial or fungal membrane vesicles, traditionally considered as microbial metabolic
wastes, are secreted mainly from the outer membrane or cell membrane of microorganisms …