Air pollution is well recognized as a major risk factor for chronic non-communicable
diseases and has been estimated to contribute more to global morbidity and mortality than …

Heavy metals exist widely in daily life, and exposure to heavy metals caused by
environmental pollution has become a serious public health problem worldwide. Due to …

The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …

Abstract Fine particulate matter< 2.5 μm (PM2. 5) air pollution is the most important
environmental risk factor contributing to global cardiovascular (CV) mortality and disability …

The blood–brain barrier (BBB) is a continuous endothelial membrane within brain
microvessels that has sealed cell-to-cell contacts and is sheathed by mural vascular cells …

Background Emerging evidence suggests that living near major roads might adversely affect
cognition. However, little is known about its relationship with the incidence of dementia …

Vascular insults can initiate a cascade of molecular events leading to neurodegeneration,
cognitive impairment, and dementia. Here, we review the cellular and molecular …

The world⿿ s population is steadily ageing and as a result, health conditions related to
ageing, such as dementia, have become a major public health concern. In 2001, it was …

None of the proposed mechanisms of Alzheimer's disease (AD) fully explains the distribution
patterns of the neuropathological changes at the cellular and regional levels, and their …

The present review synthesizes lines of emerging evidence showing how several samples
of children populations living in large cities around the world suffer to some degree neural …