Cancer-derived exosomes as novel biomarkers in metastatic gastrointestinal cancer

D Zhong, Z Wang, Z Ye, Y Wang, X Cai - Molecular Cancer, 2024 - Springer
Gastrointestinal cancer (GIC) is the most prevalent and highly metastatic malignant tumor
and has a significant impact on mortality rates. Nevertheless, the swift advancement of …

Circulating tumor cells: from new biological insights to clinical practice

X Gu, S Wei, X Lv - Signal transduction and targeted therapy, 2024 - nature.com
The primary reason for high mortality rates among cancer patients is metastasis, where
tumor cells migrate through the bloodstream from the original site to other parts of the body …

Liquid biopsy for human cancer: cancer screening, monitoring, and treatment

H Wang, Y Zhang, H Zhang, H Cao, J Mao, X Chen… - MedComm, 2024 - Wiley Online Library
Currently, tumor treatment modalities such as immunotherapy and targeted therapy have
more stringent requirements for obtaining tumor growth information and require more …

A circulating panel of circRNA biomarkers for the noninvasive and early detection of pancreatic ductal adenocarcinoma

C Xu, E Jun, Y Okugawa, Y Toiyama, E Borazanci… - Gastroenterology, 2024 - Elsevier
Background & Aims Pancreatic ductal adenocarcinoma (PDAC) is one of the most fatal
malignancies. Delayed manifestation of symptoms and lack of specific diagnostic markers …

[HTML][HTML] Overview of MicroRNAs as diagnostic and prognostic biomarkers for high-incidence cancers in 2021

C Zhang, C Sun, Y Zhao, Q Wang, J Guo, B Ye… - International journal of …, 2022 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs (ncRNAs) about 22 nucleotides in size,
which play an important role in gene regulation and are involved in almost all major cellular …

Comparative investigation of neoadjuvant immunotherapy versus adjuvant immunotherapy in perioperative patients with cancer: a global-scale, cross-sectional, and …

SB Guo, LS Hu, WJ Huang, ZZ Zhou… - … Journal of Surgery, 2024 - journals.lww.com
Background: Neoadjuvant and adjuvant immunotherapies for cancer have evolved through
a series of remarkable and critical research advances; however, addressing their similarities …

[HTML][HTML] Biomarkers in Colorectal Cancer: Actual and Future Perspectives

HD Lișcu, N Verga, DI Atasiei, DC Badiu… - International Journal of …, 2024 - mdpi.com
Biomarkers in colorectal cancer (CRC) are of great interest in the current literature due to
improvements in techniques such as liquid biopsy and next-generation sequencing (NGS) …

Liquid biopsy in lung cancer

L Li, H Jiang, B Zeng, X Wang, Y Bao, C Chen, L Ma… - Clinica Chimica …, 2024 - Elsevier
Lung cancer is a highly prevalent malignancy worldwide and the primary cause of mortality.
The absence of systematic and standardized diagnostic approaches for identifying potential …

Extracellular vesicles associated microRNAs: Their biology and clinical significance as biomarkers in gastrointestinal cancers

Y Li, S Sui, A Goel - Seminars in cancer biology, 2024 - Elsevier
Gastrointestinal (GI) cancers, including colorectal, gastric, esophageal, pancreatic, and liver,
are associated with high mortality and morbidity rates worldwide. One of the underlying …

Oral microbiota: A new insight into cancer progression, diagnosis and treatment

XL Wang, HW Xu, NN Liu - Phenomics, 2023 - Springer
The polymorphic microbiome has been defined as one of the “Hallmarks of Cancer”.
Extensive studies have now uncovered the role of oral microbiota in cancer development …