• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Importance Acute coronary syndromes (ACS) are characterized by a sudden reduction in
blood supply to the heart and include ST-segment elevation myocardial infarction (STEMI) …

Abstract Aim The “2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management
of Patients With Chronic Coronary Disease” provides an update to and consolidates new …

We report a genome-wide association study (GWAS) of coronary artery disease (CAD)
incorporating nearly a quarter of a million cases, in which existing studies are integrated with …

Background: The future risk of myocardial infarction is commonly assessed using
cardiovascular risk scores, coronary artery calcium score, or coronary artery stenosis …

Atherosclerosis, the formation of fibrofatty lesions in the artery wall, causes much morbidity
and mortality worldwide, including most myocardial infarctions and many strokes, as well as …

Many patients with chest pain undergoing coronary angiography do not show significant
obstructive coronary lesions. A substantial proportion of these patients have abnormalities in …

Coronary microvascular disease (CMD) refers to the subset of disorders affecting the
structure and function of the coronary microcirculation, is prevalent in patients across a …

Background Binary diagnosis of coronary artery disease does not preserve the complexity of
disease or quantify its severity or its associated risk with death; hence, a quantitative marker …

Background Unlike most noninvasive imaging modalities, coronary computed tomography
angiography can characterize subtypes of atherosclerotic plaque. Objectives The purpose of …