This research monograph discusses newly developed mathematical models and methods
that provide biologically meaningful inferences from data on cancer latency produced by …

In the visible world, heterogeneity typically refers to the differences that exist among
individuals in a defined population. These differences can arise from a variety of sources …

The problem of estimating parameters in the drift coefficient when a diffusion process is
observed continuously requires some specific assumptions. In this paper, we consider a …

For over a century, actuaries and biologists working independently of each other have
presented arguments for why total mortality needs to be partitioned into biologically …

Based upon the deterministic Gompertz law of cell growth, we have proposed a stochastic
model of tumour cell growth, in which the size of the tumour cells is bounded. The model …

Infectious diseases are caused by single or successive contacts with pathogens.
Nevertheless, contacts with pathogens do not implicate infection. In 1993, Yakovlev et al …

This paper discusses the distribution of tumor size at detection derived within the framework
of a new stochastic model of carcinogenesis. This distribution assumes a simple limiting …

This paper is concerned with some versions of a stochastic model of aging proposed
recently by TYURIN et al.(1993). In contrast to the commonly used Gompertz-Makeham …

In some clinical applications in oncology randomized, double armed, and double-blind trials
are not possible. In case of device applications, double-blinded conditions are nonrealistic …

In order to assure hygiene safety for patients, optimal use of drugs is necessary for
controlling the number of clinically observed tumor cells. Based on a mathematical model of …