Host and viral determinants of influenza A virus species specificity

JS Long, B Mistry, SM Haslam… - Nature Reviews …, 2019‏ - nature.com
Influenza A viruses cause pandemics when they cross between species and an
antigenically novel virus acquires the ability to infect and transmit between these new hosts …

Zoonotic animal influenza virus and potential mixing vessel hosts

EM Abdelwhab, TC Mettenleiter - Viruses, 2023‏ - mdpi.com
Influenza viruses belong to the family Orthomyxoviridae with a negative-sense, single-
stranded segmented RNA genome. They infect a wide range of animals, including humans …

Sialic acid receptor specificity in mammary gland of dairy cattle infected with highly pathogenic avian influenza A (H5N1) virus

RK Nelli, TA Harm, C Siepker… - Emerging Infectious …, 2024‏ - pmc.ncbi.nlm.nih.gov
In March 2024, the US Department of Agriculture's Animal and Plant Health Inspection
Service reported detection of highly pathogenic avian influenza (HPAI) A (H5N1) virus in …

[HTML][HTML] Influence of host sialic acid receptors structure on the host specificity of influenza viruses

C Zhao, J Pu - Viruses, 2022‏ - mdpi.com
Influenza viruses need to use sialic acid receptors to invade host cells, and the α-2, 3 and α-
2, 6 sialic acids glycosidic bonds linking the terminal sialic acids are generally considered to …

Role of receptor binding specificity in influenza A virus transmission and pathogenesis

M de Graaf, RAM Fouchier - The EMBO journal, 2014‏ - embopress.org
The recent emergence of a novel avian A/H 7 N 9 influenza virus in poultry and humans in C
hina, as well as laboratory studies on adaptation and transmission of avian A/H 5 N 1 …

Influenza and SARS-coronavirus activating proteases TMPRSS2 and HAT are expressed at multiple sites in human respiratory and gastrointestinal tracts

S Bertram, A Heurich, H Lavender, S Gierer, S Danisch… - PloS one, 2012‏ - journals.plos.org
The type II transmembrane serine proteases TMPRSS2 and HAT activate influenza viruses
and the SARS-coronavirus (TMPRSS2) in cell culture and may play an important role in viral …

An overview of influenza A virus genes, protein functions, and replication cycle highlighting important updates

RP Chauhan, ML Gordon - Virus genes, 2022‏ - Springer
The recent research findings on influenza A virus (IAV) genome biology prompted us to
present a comprehensive overview of IAV genes, protein functions, and replication cycle …

The interplay between the host receptor and influenza virus hemagglutinin and neuraminidase

L Byrd-Leotis, RD Cummings… - International journal of …, 2017‏ - mdpi.com
The hemagglutinin (HA) and neuraminidase (NA) glycoproteins of influenza A virus are
responsible for the surface interactions of the virion with the host. Entry of the virus is …

Rotavirus interactions with host intestinal epithelial cells

JO Amimo, SA Raev, J Chepngeno… - Frontiers in …, 2021‏ - frontiersin.org
Rotavirus (RV) is the foremost enteric pathogen associated with severe diarrheal illness in
young children (< 5years) and animals worldwide. RV primarily infects mature enterocytes in …

The role of receptor binding specificity in interspecies transmission of influenza viruses

M Imai, Y Kawaoka - Current opinion in virology, 2012‏ - Elsevier
Influenza A virus infection begins with the binding of the hemagglutinin (HA) glycoprotein to
sialic acid-containing receptors on the surface of the target cell. Avian influenza viruses …