Withania somnifera: Progress towards a Pharmaceutical Agent for Immunomodulation and Cancer Therapeutics
Chemotherapy is one of the prime treatment options for cancer. However, the key issues
with traditional chemotherapy are recurrence of cancer, development of resistance to …
with traditional chemotherapy are recurrence of cancer, development of resistance to …
[HTML][HTML] Etiology of lung carcinoma and treatment through medicinal plants, marine plants and green synthesized nanoparticles: A comprehensive review
P Chaudhary, P Janmeda, A Pareek… - Biomedicine & …, 2024 - Elsevier
Lung cancer, a leading global cause of mortality, poses a significant public health challenge
primarily linked to tobacco use. While tobacco contributes to over 90% of cases, factors like …
primarily linked to tobacco use. While tobacco contributes to over 90% of cases, factors like …
Targeting transforming growth factor‐ß signalling for cancer prevention and intervention: Recent advances in develo** small molecules of natural origin
D Tewari, A Priya, A Bishayee… - Clinical and …, 2022 - Wiley Online Library
Background Cancer is the world's second leading cause of death, but a significant
advancement in cancer treatment has been achieved within the last few decades. However …
advancement in cancer treatment has been achieved within the last few decades. However …
Withaferin A: A Pleiotropic Anticancer Agent from the Indian Medicinal Plant Withania somnifera (L.) Dunal
Cancer represents the second most deadly disease and one of the most important public
health concerns worldwide. Surgery, chemotherapy, radiation therapy, and immune therapy …
health concerns worldwide. Surgery, chemotherapy, radiation therapy, and immune therapy …
An updated review on phytochemistry and molecular targets of Withania somnifera (L.) Dunal (Ashwagandha)
Withania somnifera (L.) Dunal belongs to the nightshade family Solanaceae and is
commonly known as Ashwagandha. It is pharmacologically a significant medicinal plant of …
commonly known as Ashwagandha. It is pharmacologically a significant medicinal plant of …
[HTML][HTML] Covalent binding of withanolides to cysteines of protein targets
C Bailly - Biochemical Pharmacology, 2024 - Elsevier
Withanolides represent an important category of natural products with a steroidal lactone
core. Many of them contain an α, β-unsaturated carbonyl moiety with a high reactivity toward …
core. Many of them contain an α, β-unsaturated carbonyl moiety with a high reactivity toward …
Withaferin A: A potential selective glucocorticoid receptor modulator with anti-inflammatory effect
Y Liang, Q Jiang, H Zou, J Zhao, J Zhang… - Food and Chemical …, 2023 - Elsevier
Glucocorticoids have been widely applied to various clinical treatment, however some
serious side effects may occur during the treatment. It is widely known that glucocorticoids …
serious side effects may occur during the treatment. It is widely known that glucocorticoids …
Medicinal Characteristics of Withania somnifera L. in Colorectal Cancer Management
JM Macharia, Z Káposztás, RL Bence - Pharmaceuticals, 2023 - mdpi.com
Research into tumorigenic pathways can aid in the development of more efficient cancer
therapies and provide insight into the physiological regulatory mechanisms employed by …
therapies and provide insight into the physiological regulatory mechanisms employed by …
Ethnological validation of Ashwagandha (Withania somnifera L. Dunal) ghrita as 'Vajikarana Rasayana': In-silico, in-vitro and in-vivo approach
Ethnopharmacological relevance Processing cow ghee (clarified butterfat) with therapeutic
herbs, ie ghrita, is recognized for augmenting the therapeutic efficacy of plant materials …
herbs, ie ghrita, is recognized for augmenting the therapeutic efficacy of plant materials …
Hairy root cultures of Physalis minima L. — an alternative source of withaferin A production
Physalis minima L. is an important yet underutilised medicinal plant. It has many medicinal
properties, including anticancer activity. This plant synthesizes a crucial steroidal lactone …
properties, including anticancer activity. This plant synthesizes a crucial steroidal lactone …