Mechanism of antimicrobial peptides: antimicrobial, anti-inflammatory and antibiofilm activities

Y Luo, Y Song - International journal of molecular sciences, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are regarded as a new generation of antibiotics. Besides
antimicrobial activity, AMPs also have antibiofilm, immune-regulatory, and other activities …

Antimicrobial peptides: an update on classifications and databases

A Bin Hafeez, X Jiang, PJ Bergen, Y Zhu - International journal of …, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

[HTML][HTML] A review on the screening methods for the discovery of natural antimicrobial peptides

B Yang, H Yang, J Liang, J Chen, C Wang… - Journal of …, 2024 - Elsevier
Natural antimicrobial peptides (AMPs) are promising candidates for the development of a
new generation of antimicrobials to combat antibiotic-resistant pathogens. They have found …

Exploring the potential of bioactive peptides: From natural sources to therapeutics

K Purohit, N Reddy, A Sunna - International Journal of Molecular …, 2024 - mdpi.com
Bioactive peptides, specific protein fragments with positive health effects, are gaining
traction in drug development for advantages like enhanced penetration, low toxicity, and …

Cystic fibrosis and Pseudomonas aeruginosa: the host-microbe interface

S Malhotra, D Hayes Jr, DJ Wozniak - Clinical microbiology …, 2019 - journals.asm.org
In human pathophysiology, the clash between microbial infection and host immunity
contributes to multiple diseases. Cystic fibrosis (CF) is a classical example of this …

Intracellular delivery by membrane disruption: mechanisms, strategies, and concepts

MP Stewart, R Langer, KF Jensen - Chemical reviews, 2018 - ACS Publications
Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Advances of peptides for antibacterial applications

Y Yan, Y Li, Z Zhang, X Wang, Y Niu, S Zhang… - Colloids and Surfaces B …, 2021 - Elsevier
In the past few decades, peptide antibacterial products with unique antibacterial
mechanisms have attracted widespread interest. They can effectively reduce the probability …

Membrane active antimicrobial peptides: translating mechanistic insights to design

J Li, JJ Koh, S Liu, R Lakshminarayanan… - Frontiers in …, 2017 - frontiersin.org
Antimicrobial peptides (AMPs) are promising next generation antibiotics that hold great
potential for combating bacterial resistance. AMPs can be both bacteriostatic and …

Intracellular targeting mechanisms by antimicrobial peptides

CF Le, CM Fang, SD Sekaran - Antimicrobial agents and …, 2017 - journals.asm.org
Antimicrobial peptides (AMPs) are expressed in various living organisms as first-line host
defenses against potential harmful encounters in their surroundings. AMPs are short …

Membrane targeting cationic antimicrobial peptides

D Ciumac, H Gong, X Hu, JR Lu - Journal of colloid and interface science, 2019 - Elsevier
Many short cationic peptides are amphiphilic and are often termed antimicrobial peptides
(AMPs) as they can kill various microorganisms. These AMPs have largely been discovered …