Emerging technologies in algal biotechnology: toward the establishment of a sustainable, algae-based bioeconomy

M Fabris, RM Abbriano, M Pernice… - Frontiers in plant …, 2020 - frontiersin.org
Mankind has recognized the value of land plants as renewable sources of food, medicine,
and materials for millennia. Throughout human history, agricultural methods were …

Lipid biomarkers: molecular tools for illuminating the history of microbial life

RE Summons, PV Welander, DA Gold - Nature Reviews Microbiology, 2022 - nature.com
Fossilized lipids preserved in sedimentary rocks offer singular insights into the Earth's
palaeobiology. These 'biomarkers' encode information pertaining to the oxygenation of the …

Lost world of complex life and the late rise of the eukaryotic crown

JJ Brocks, BJ Nettersheim, P Adam, P Schaeffer… - Nature, 2023 - nature.com
Eukaryotic life appears to have flourished surprisingly late in the history of our planet. This
view is based on the low diversity of diagnostic eukaryotic fossils in marine sediments of mid …

Expanding the insight of ecological risk on the novel chiral pesticide mefentrifluconazole: Mechanism of enantioselective toxicity to earthworms (Eisenia fetida)

X Yao, C Liang, H Lv, W Liu, Q Wang, J Ding… - Journal of Hazardous …, 2024 - Elsevier
Continued application of new chiral fungicide mefentrifluconazole (MFZ) increases its risk to
soil ecosystem. However, the toxicity of MFZ enantiomers to soil fauna and whether …

Squalene monooxygenase: a journey to the heart of cholesterol synthesis

NK Chua, HW Coates, AJ Brown - Progress in lipid research, 2020 - Elsevier
Squalene monooxygenase (SM) is a vital sterol synthesis enzyme across eukaryotic life. In
yeast, it is a therapeutic target for treating certain fungal infections, and in mammals it is a …

Brassinosteroid biosynthesis and signaling: Conserved and diversified functions of core genes across multiple plant species

B Zebosi, E Vollbrecht, NB Best - Plant Communications, 2024 - cell.com
Brassinosteroids (BRs) are important regulators that control myriad aspects of plant growth
and development, including biotic and abiotic stress responses, such that modulating BR …

Simultaneous production of DHA and squalene from Aurantiochytrium sp. grown on forest biomass hydrolysates

A Patel, U Rova, P Christakopoulos… - Biotechnology for …, 2019 - Springer
Background Recent evidence points to the nutritional importance of docosahexaenoic acid
(DHA) in the human diet. Thraustochytrids are heterotrophic marine oleaginous …

Co-production of DHA and squalene by thraustochytrid from forest biomass

A Patel, S Liefeldt, U Rova, P Christakopoulos… - Scientific Reports, 2020 - nature.com
Omega-3 fatty acids, and specifically docosahexaenoic acid (DHA), are important and
essential nutrients for human health. Thraustochytrids are recognised as commercial strains …

[HTML][HTML] Perspectives for glyco-engineering of recombinant biopharmaceuticals from microalgae

L Barolo, RM Abbriano, AS Commault, J George… - Cells, 2020 - mdpi.com
Microalgae exhibit great potential for recombinant therapeutic protein production, due to
lower production costs, immunity to human pathogens, and advanced genetic toolkits …

Extrachromosomal Genetic Engineering of the Marine Diatom Phaeodactylum tricornutum Enables the Heterologous Production of Monoterpenoids

M Fabris, J George, U Kuzhiumparambil… - ACS synthetic …, 2020 - ACS Publications
Geraniol is a commercially relevant plant-derived monoterpenoid that is a main component
of rose essential oil and used as insect repellent. Geraniol is also a key intermediate …