Increasing evidence suggests that renal inflammation contributes to the pathogenesis and
progression of diabetic kidney disease (DKD) and that anti-inflammatory therapies might …

Renal tubules are the major component of the kidney and are vulnerable to a variety of
injuries including hypoxia, proteinuria, toxins, metabolic disorders, and senescence. It has …

Tubulointerstitial abnormalities are predictive of the progression of diabetic kidney disease
(DKD), and their targeting may be an effective means for prevention. Proximal tubular (PT) …

Diabetic kidney disease (DKD) is a devastating microvascular complication associated with
diabetes mellitus. Recently, the major focus of glomerular lesions of DKD has partly shifted …

Dysregulation of autophagy in diabetic kidney disease (DKD) has been reported, but the
underlying mechanism and its pathogenic role remain elusive. We show that autophagy was …

Diabetic nephropathy (DN) is a common complication of Diabetes Mellitus (DM) Types 1 and
2, and prevention of end stage renal disease (ESRD) remains a major challenge. Despite its …

Diabetic kidney disease (DKD) is a chronic complication of diabetes and the leading cause
of end-stage renal disease (ESRD) worldwide. Currently, there are limited therapeutic drugs …

Albuminuria, a hallmark of diabetic nephropathy, reflects not only injury and dysfunction of
the filtration apparatus, but is also affected by altered glomerular hemodynamics and …