Highly selective binding of organometallic ruthenium ethylenediamine complexes to nucleic acids: novel recognition mechanisms

H Chen, JA Parkinson, RE Morris… - Journal of the American …, 2003 - ACS Publications
We have investigated the recognition of nucleic acid derivatives by organometallic
ruthenium (II) arene anticancer complexes of the type [(η6-arene) Ru (II)(en) X] where en …

Anion template effect on the self-assembly and interconversion of metallacyclophanes

CS Campos-Fernández, BL Schottel… - Journal of the …, 2005 - ACS Publications
Reactions of 3, 6-bis (2-pyridyl)-1, 2, 4, 5-tetrazine (bptz) with solvated first-row transition
metals M (II)(M (II)= Ni, Zn, Mn, Fe, Cu) have been explored with emphasis on the factors that …

Anion− π interactions as controlling elements in self-assembly reactions of Ag (I) complexes with π-acidic aromatic rings

BL Schottel, HT Chifotides, M Shatruk… - Journal of the …, 2006 - ACS Publications
Reactions of 3, 6-bis (2 '-pyridyl)-1, 2, 4, 5-tetrazine (bptz) and 3, 6-bis (2 '-pyridyl)-1, 2-
pyridazine (bppn) with the AgX salts (X=[PF6]-,[AsF6]-,[SbF6]-, and [BF4]-) afford complexes …

Molecular origin of the sequence-dependent kinetics of reactions between cisplatin derivatives and DNA

J Kozelka - Inorganica Chimica Acta, 2009 - Elsevier
Experimental and theoretical studies related to the kinetics of interactions between cisplatin
derivatives and DNA are critically reviewed. The reaction between DNA and cisplatin is a …

Riboflavin as a Bioorthogonal Photocatalyst for the Activation of a Pt IV Prodrug

S Alonso-de Castro, E Ruggiero, A Ruiz-de-Angulo… - Chemical …, 2017 - pubs.rsc.org
Encouraging developments demonstrate that few transition metal and organometallic
catalysts can operate in a bioorthogonal fashion and promote non-natural chemistry in living …

Compostos de platina em quimioterapia do câncer

APS Fontes, SG Almeida, LA Nader - Química Nova, 1997 - SciELO Brasil
The vast majority of clinically used antitumor drugs are either synthetic or natural product
based organic compounds. In this review we describe different aspects, such as structure …

Crystal and Molecular Structures of Asymmetric cis- and trans-Platinum(II/IV) Compounds and Their Reactions with DNA Fragments

EG Talman, W Brüning, J Reedijk, AL Spek… - Inorganic …, 1997 - ACS Publications
The asymmetrically substituted platinum (II) complexes cis-Pt (NH3)(c-C6H11NH2) Cl2 and
trans-Pt (NH3)(c-C6H11NH2) Cl2 have been synthesized and their crystal structures have …

New isomeric azine-bridged dinuclear platinum (II) complexes circumvent cross-resistance to cisplatin

S Komeda, GV Kalayda, M Lutz, AL Spek… - Journal of medicinal …, 2003 - ACS Publications
Four new isomeric azine-bridged complexes ([{cis-Pt (NH3) 2Cl} 2 (μ-pzn)] Cl2 (1a)(pzn=
pyrazine) and its corresponding nitrate salt (1b),[{cis-Pt (NH3) 2Cl} 2 (μ-pmn)] Cl2 (2)(pmn …

Drug Delivery with a Calixpyrrole–trans-Pt(II) Complex

G Cafeo, G Carbotti, A Cuzzola, M Fabbi… - Journal of the …, 2013 - ACS Publications
A meso-p-nitroaniline-calix [4] pyrrole derivative trans-coordinated to a Pt (II) center was
synthesized and its structure solved by X-ray analysis. Adenosine monophosphate (AMP) …

Titanium (IV) targets phosphoesters on nucleotides: implications for the mechanism of action of the anticancer drug titanocene dichloride

M Guo, Z Guo, P Sadler - JBIC Journal of Biological Inorganic Chemistry, 2001 - Springer
Reactions between the anticancer drug titanocene dichloride (Cp 2 TiCl 2) and various
nucleotides and their constituents in aqueous solution or N, N-dimethylformamide (DMF) …