Ovarian damage from chemotherapy and current approaches to its protection
N Spears, F Lopes, A Stefansdottir… - Human reproduction …, 2019 - academic.oup.com
Background Anti-cancer therapy is often a cause of premature ovarian insufficiency and
infertility since the ovarian follicle reserve is extremely sensitive to the effects of …
infertility since the ovarian follicle reserve is extremely sensitive to the effects of …
Mechanisms of cell death in oxidative stress
SW Ryter, HP Kim, A Hoetzel, JW Park… - Antioxidants & redox …, 2007 - liebertpub.com
Reactive oxygen or nitrogen species (ROS/RNS) generated endogenously or in response to
environmental stress have long been implicated in tissue injury in the context of a variety of …
environmental stress have long been implicated in tissue injury in the context of a variety of …
Tumor response to radiotherapy regulated by endothelial cell apoptosis
About 50% of cancer patients receive radiation therapy. Here we investigated the hypothesis
that tumor response to radiation is determined not only by tumor cell phenotype but also by …
that tumor response to radiation is determined not only by tumor cell phenotype but also by …
Biologically active sphingolipids in cancer pathogenesis and treatment
Biologically active sphingolipids have key roles in the regulation of several fundamental
biological processes that are integral to cancer pathogenesis. Recent significant progress in …
biological processes that are integral to cancer pathogenesis. Recent significant progress in …
ICRP publication 118: ICRP statement on tissue reactions and early and late effects of radiation in normal tissues and organs–threshold doses for tissue reactions in a …
FA Stewart, AV Akleyev, M Hauer-Jensen, JH Hendry… - Annals of the ICRP, 2012 - Elsevier
This report provides a review of early and late effects of radiation in normal tissues and
organs with respect to radiation protection. It was instigated following a recommendation in …
organs with respect to radiation protection. It was instigated following a recommendation in …
Fertility preservation for young patients with cancer: who is at risk and what can be offered?
Estimates suggest that by 2010, one in 715 people in the UK will have survived cancer
during childhood. With increasing numbers of children cured, attention has focused on their …
during childhood. With increasing numbers of children cured, attention has focused on their …
Molecular targets of epigallocatechin—Gallate (EGCG): A special focus on signal transduction and cancer
Green tea is a beverage that is widely consumed worldwide and is believed to exert effects
on different diseases, including cancer. The major components of green tea are catechins, a …
on different diseases, including cancer. The major components of green tea are catechins, a …
Chemotherapy-induced damage to ovary: mechanisms and clinical impact
Cancer is a major public health problem around the world. Currently, about 5% of women
diagnosed with cancer are of reproductive age. These young survivors may face …
diagnosed with cancer are of reproductive age. These young survivors may face …
Essential role for sphingosine kinases in neural and vascular development
K Mizugishi, T Yamashita, A Olivera… - … and cellular biology, 2005 - Taylor & Francis
Sphingosine-1-phosphate (S1P), an important sphingolipid metabolite, regulates diverse
cellular processes, including cell survival, growth, and differentiation. Here we show that …
cellular processes, including cell survival, growth, and differentiation. Here we show that …
Lysophospholipid receptors: signaling and biology
▪ Abstract Lysophospholipids (LPs), such as lysophosphatidic acid and sphingosine 1-
phosphate, are membrane-derived bioactive lipid mediators. LPs can affect fundamental …
phosphate, are membrane-derived bioactive lipid mediators. LPs can affect fundamental …