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Liposomal formulations of photosensitizers
Photodynamic therapy (PDT) is a clinical ablation modality to treat cancers and other
diseases. PDT involves administration of a photosensitizer, followed by irradiation of target …
diseases. PDT involves administration of a photosensitizer, followed by irradiation of target …
The Photosensitizer Temoporfin (mTHPC) – Chemical, Pre‐clinical and Clinical Developments in the Last Decade†‡
This review follows the research, development and clinical applications of the
photosensitizer 5, 10, 15, 20‐tetra (m‐hydroxyphenyl) chlorin (m THPC, temoporfin) in …
photosensitizer 5, 10, 15, 20‐tetra (m‐hydroxyphenyl) chlorin (m THPC, temoporfin) in …
Current state of the nanoscale delivery systems for temoporfin-based photodynamic therapy: Advanced delivery strategies
Enthusiasm for photodynamic therapy (PDT) as a promising technique to eradicate various
cancers has increased exponentially in recent decades. The majority of clinically approved …
cancers has increased exponentially in recent decades. The majority of clinically approved …
Bioluminescence resonance energy transfer using luciferase-immobilized quantum dots for self-illuminated photodynamic therapy
Photodynamic therapy (PDT) is an innovative method for cancer treatment that involves the
administration of a photosensitizing agent followed by exposure to visible light. An …
administration of a photosensitizing agent followed by exposure to visible light. An …
Improved in vivo delivery of m-THPC via pegylated liposomes for use in photodynamic therapy
Pegylated liposomal nanocarriers have been developed with the aim of achieving improved
uptake of the clinical PDT photosensitiser, m-THPC, into target tissues through increased …
uptake of the clinical PDT photosensitiser, m-THPC, into target tissues through increased …
Strategies for optimizing the delivery to tumors of macrocyclic photosensitizers used in photodynamic therapy (PDT)
This review briefly summaries the principles and mechanisms of action of photodynamic
therapy (PDT) as concerns its application in the oncological field, highlighting its drawbacks …
therapy (PDT) as concerns its application in the oncological field, highlighting its drawbacks …
Current status of liposomal porphyrinoid photosensitizers
Highlights•Liposomes as highly potent carriers for porphyrinoid photosensitizer
delivery.•Visudyne®–the first commercially available liposomal photosensitizer.• …
delivery.•Visudyne®–the first commercially available liposomal photosensitizer.• …
Porphyrin Macrocycles: General Properties and Theranostic Potential
R Boscencu, N Radulea, G Manda, IF Machado… - Molecules, 2023 - mdpi.com
Despite specialists' efforts to find the best solutions for cancer diagnosis and therapy, this
pathology remains the biggest health threat in the world. Global statistics concerning deaths …
pathology remains the biggest health threat in the world. Global statistics concerning deaths …
[HTML][HTML] Uptake and photo-toxicity of Foscan®, Foslip® and Fospeg® in multicellular tumor spheroids
In cancer photodynamic therapy (PDT), an efficient and homogeneous intratumoral
accumulation of the photosensitizer (PS) is required to induce cell damages in the entire …
accumulation of the photosensitizer (PS) is required to induce cell damages in the entire …
Photodynamic and antiangiogenic activities of parietin liposomes in triple negative breast cancer
Parietin (PTN) is an anthraquinone with promising efficacy in the inhibition of cancer cell
proliferation and tumor growth. Due to its hydrophobicity, PTN is sparingly soluble under …
proliferation and tumor growth. Due to its hydrophobicity, PTN is sparingly soluble under …