Lipoprotein (a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement

F Kronenberg, S Mora, ESG Stroes… - European heart …, 2022 - academic.oup.com
Abstract This 2022 European Atherosclerosis Society lipoprotein (a)[Lp (a)] consensus
statement updates evidence for the role of Lp (a) in atherosclerotic cardiovascular disease …

Lipoprotein (a): knowns, unknowns and uncertainties

M Ruscica, CR Sirtori, A Corsini, GF Watts… - Pharmacological …, 2021 - Elsevier
Over the last 10 years, there have been advances on several aspects of lipoprotein (a)
which are reviewed in the present article. Since the standard immunoassays for measuring …

Recent advances in demystifying the metabolism of lipoprotein (a)

K Chemello, DC Chan, G Lambert, GF Watts - Atherosclerosis, 2022 - Elsevier
Abstract Lipoprotein (a)(Lp (a)) is a strange lipoprotein species causatively independently
and significantly associated with cardiovascular diseases and calcified aortic valve stenosis …

Uncoupling the vicious cycle of mechanical stress and inflammation in calcific aortic valve disease

NH Dayawansa, S Baratchi, K Peter - Frontiers in Cardiovascular …, 2022 - frontiersin.org
Calcific aortic valve disease (CAVD) is a common acquired valvulopathy, which carries a
high burden of mortality. Chronic inflammation has been postulated as the predominant …

[Retracted] Identification of MMP9 as a Novel Biomarker to Mitochondrial Metabolism Disorder and Oxidative Stress in Calcific Aortic Valve Stenosis

C Liu, R Liu, Z Cao, Q Guo, H Huang… - Oxidative Medicine …, 2022 - Wiley Online Library
Calcific aortic valve stenosis (CAVS) is the most common heart valve disorder among
humans. To date, no effective method has been identified to prevent this disease. Herein, we …

Aortic stenosis risk in rheumatoid arthritis

TM Johnson, CA Mahabir, Y Yang, P Roul… - JAMA internal …, 2023 - jamanetwork.com
Importance Although an increased risk of ischemic cardiovascular disease has been
associated with rheumatoid arthritis (RA), the risk of aortic stenosis (AS) is unknown …

Integrated proteomic and metabolomic profile analyses of cardiac valves revealed molecular mechanisms and targets in calcific aortic valve disease

B Fu, J Wang, L Wang, Q Wang, Z Guo… - Frontiers in …, 2022 - frontiersin.org
Background This study aimed to define changes in the metabolic and protein profiles of
patients with calcific aortic valve disease (CAVD). Methods and results We analyzed cardiac …

Lipoprotein (a) in cardiovascular diseases: insight from a bibliometric study

D Šuran, H Blažun Vošner, J Završnik… - Frontiers in Public …, 2022 - frontiersin.org
Lipoprotein (a)[Lp (a)] is a complex polymorphic lipoprotein comprised of a low-density
lipoprotein particle with one molecule of apolipoprotein B100 and an additional …

Circulating plasma proteins in aortic stenosis: Associations with severity, myocardial response, and clinical outcomes

ESJ Tan, H Choi, CR DeFilippi, YY Oon… - Journal of the …, 2024 - ahajournals.org
Background Echocardiographic indexes of aortic stenosis may not comprehensively reflect
disease morbidity. Plasma proteomic profiling may add prognostic value in these patients …

Multiomics identification of ALDH9A1 as a crucial immunoregulatory molecule involved in calcific aortic valve disease

LZ Chen, PF Zheng, XJ Shi - Scientific Reports, 2024 - nature.com
Mitochondrial dysfunction and immune cell infiltration play crucial yet incompletely
understood roles in the pathogenesis of calcific aortic valve disease (CAVD). This study …