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MALDI TOF imaging mass spectrometry in clinical pathology: a valuable tool for cancer diagnostics
Matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) imaging mass
spectrometry (IMS) is an evolving technique in cancer diagnostics and combines the …
spectrometry (IMS) is an evolving technique in cancer diagnostics and combines the …
Diagnostic utility of molecular and imaging biomarkers in cytological indeterminate thyroid nodules
Indeterminate thyroid cytology (Bethesda III and IV) corresponds to follicular-patterned
benign and malignant lesions, which are particularly difficult to differentiate on cytology …
benign and malignant lesions, which are particularly difficult to differentiate on cytology …
MALDI mass spectrometry imaging: A cutting‐edge tool for fundamental and clinical histopathology
R Longuespée, R Casadonte… - PROTEOMICS …, 2016 - Wiley Online Library
Histopathological diagnoses have been done in the last century based on hematoxylin and
eosin staining. These methods were complemented by histochemistry, electron microscopy …
eosin staining. These methods were complemented by histochemistry, electron microscopy …
Applications of mass spectrometry imaging to cancer
Pathologists play an essential role in the diagnosis and prognosis of benign and cancerous
tumors. Clinicians provide tissue samples, for example, from a biopsy, which are then …
tumors. Clinicians provide tissue samples, for example, from a biopsy, which are then …
A MALDI-Mass Spectrometry Imaging method applicable to different formalin-fixed paraffin-embedded human tissues
Recent advancements in Matrix Assisted Laser Desorption/Ionisation (MALDI) Mass
Spectrometry Imaging (MSI) technology have enabled the analysis of formalin-fixed paraffin …
Spectrometry Imaging (MSI) technology have enabled the analysis of formalin-fixed paraffin …
Applications of spatially resolved omics in the field of endocrine tumors
Y Hou, Y Gao, S Guo, Z Zhang, R Chen… - Frontiers in …, 2023 - frontiersin.org
Endocrine tumors derive from endocrine cells with high heterogeneity in function, structure
and embryology, and are characteristic of a marked diversity and tissue heterogeneity …
and embryology, and are characteristic of a marked diversity and tissue heterogeneity …
Molecular signatures of medullary thyroid carcinoma by matrix-assisted laser desorption/ionisation mass spectrometry imaging
The main aim of the study was to assess the feasibility of matrix-assisted laser
desorption/ionisation mass spectrometry imaging (MALDI-MSI) in the pathological …
desorption/ionisation mass spectrometry imaging (MALDI-MSI) in the pathological …
[HTML][HTML] Cytomolecular classification of thyroid nodules using fine-needle washes aspiration biopsies
Fine-needle aspiration biopsies (FNA) represent the gold standard to exclude the malignant
nature of thyroid nodules. After cytomorphology, 20–30% of cases are deemed …
nature of thyroid nodules. After cytomorphology, 20–30% of cases are deemed …
[HTML][HTML] Molecular profiles of thyroid cancer subtypes: Classification based on features of tissue revealed by mass spectrometry imaging
Determination of the specific type of thyroid cancer is crucial for the prognosis and selection
of treatment of this malignancy. However, in some cases appropriate classification is not …
of treatment of this malignancy. However, in some cases appropriate classification is not …
[HTML][HTML] MALDI-MSI as a Complementary diagnostic tool in cytopathology: a pilot study for the characterization of thyroid nodules
The present study applies for the first time as Matrix-Assisted Laser Desorption/Ionization
(MALDI) Mass Spectrometry Imaging (MSI) on real thyroid Fine Needle Aspirations (FNAs) to …
(MALDI) Mass Spectrometry Imaging (MSI) on real thyroid Fine Needle Aspirations (FNAs) to …