Fundamental importance of ionic interactions in the liquid phase: A review of recent studies of ionic liquids in biomedical and pharmaceutical applications

KS Egorova, VP Ananikov - Journal of Molecular Liquids, 2018 - Elsevier
In recent years, research on ions and ionic interactions in solution has become a leading
scientific direction, and this advance has been especially pronounced in the field of ionic …

Greasing the wheels of lipid biology with chemical tools

TW Bumpus, JM Baskin - Trends in biochemical sciences, 2018 - cell.com
Biological lipids are a structurally diverse and historically vexing group of hydrophobic
metabolites. Here, we review recent advances in chemical imaging techniques that reveal …

Live‐Cell Imaging of Sterculic Acid—a Naturally Occurring 1, 2‐Cyclopropene Fatty Acid—by Bioorthogonal Reaction with Turn‐On Tetrazine‐Fluorophore …

K Bertheussen, M van de Plassche… - Angewandte Chemie …, 2022 - Wiley Online Library
In the field of lipid research, bioorthogonal chemistry has made the study of lipid uptake and
processing in living systems possible, whilst minimising biological properties arising from …

Combining lipid-mimicking-enabled transition metal and enzyme-mediated catalysis at the cell surface of E. coli

T Wegner, A Dombovski, K Gesing, A Köhrer… - Chemical …, 2023 - pubs.rsc.org
Being an essential multifunctional platform and interface to the extracellular environment,
the cell membrane constitutes a valuable target for the modification and manipulation of …

Ionic liquids meet lipid bilayers: A state-of-the-art review

A Benedetto - Biophysical Reviews, 2023 - Springer
In the past 25 years, a vast family of complex organic salts known as room-temperature ionic
liquids (ILs) has received increasing attention due to their potential applications. ILs are …

The debut of chiral cyclic (alkyl)(amino) carbenes (CAACs) in enantioselective catalysis

D Pichon, M Soleilhavoup, J Morvan, GP Junor… - Chemical …, 2019 - pubs.rsc.org
The popularity of NHCs in transition metal catalysis has prompted the development of chiral
versions as electron-rich neutral stereodirecting ancillary ligands for enantioselective …

P-selectin-dependent leukocyte adhesion is governed by endolysosomal two-pore channel 2

J Goretzko, I Pauels, N Heitzig, K Thomas, M Kardell… - Cell Reports, 2023 - cell.com
Upon proinflammatory challenges, endothelial cell surface presentation of the leukocyte
receptor P-selectin, together with the stabilizing co-factor CD63, is needed for leukocyte …

Synthetic Lipid Biology

PHB Chen, XL Li, JM Baskin - Chemical Reviews, 2025 - ACS Publications
Cells contain thousands of different lipids. Their rapid and redundant metabolism, dynamic
movement, and many interactions with other biomolecules have justly earned lipids a …

NTA-cholesterol analogue for the nongenetic liquid-ordered phase-specific functionalization of lipid membranes with proteins

Y Zheng, T Wegner, D Di Iorio, M Pierau… - ACS Chemical …, 2023 - ACS Publications
The nongenetic modification of cell membranes with proteins is a straightforward way of
cellular engineering. In these processes, it is important to specifically address the proteins to …

Lipid mimetics: a versatile toolbox for lipid biology and beyond

T Wegner, R Laskar, F Glorius - Current Opinion in Chemical Biology, 2022 - Elsevier
Being the principal component of biological membranes lipids are essential building blocks
of life. Given their huge biological importance, the investigation of lipids, their properties …