Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies

A Thakur, R Singla, V Jaitak - European journal of medicinal chemistry, 2015 - Elsevier
Coumarins are fused benzene and pyrone ring systems which prompt biological
investigation to assess their potential therapeutic significance. It possesses immeasurable …

The use of plant extracts and their phytochemicals for control of toxigenic fungi and mycotoxins

R Makhuvele, K Naidu, S Gbashi, VC Thipe, OA Adebo… - Heliyon, 2020 - cell.com
Mycotoxins present a great concern to food safety and security due to their adverse health
and socio-economic impacts. The necessity to formulate novel strategies that can mitigate …

Evidence of some natural products with antigenotoxic effects. Part 2: plants, vegetables, and natural resin

D López-Romero, JA Izquierdo-Vega… - Nutrients, 2018 - mdpi.com
Cancer is one of the leading causes of death worldwide. The agents capable of causing
damage to genetic material are known as genotoxins and, according to their mode of action …

Lansium domesticum—A Fruit with Multi-Benefits: Traditional Uses, Phytochemicals, Nutritional Value, and Bioactivities

HM Abdallah, GA Mohamed, SRM Ibrahim - Nutrients, 2022 - mdpi.com
Lansium domesticum (Langsat, Meliaceae) is a tropical fruit mainly found in Southeast Asian
countries, particularly in Thailand, Malaysia, Indonesia, and the Philippines. Traditionally, it …

Dynamic degradation of penconazole and its effect on antioxidant enzyme activity and malondialdehyde content in apple fruit

Y Li, L Han, B Wang, J Zhang, J Nie - Scientia Horticulturae, 2022 - Elsevier
The fungicide penconazole is often applied to prevent fungal diseases and improve fruit
quality and yield in apple production. However, the impact of penconazole on apple quality …

Investigation of the Genotoxic, Antigenotoxic and Antioxidant Profile of Different Extracts from Equisetum arvense L.

M Dormousoglou, I Efthimiou, M Antonopoulou… - Antioxidants, 2022 - mdpi.com
The present study investigated the cyto-genotoxic and antigenotoxic effects of four different
extracts of Equisetum arvense L.(common name: field horsetail) on human lymphocytes …

In vitro antioxidant assessment, screening of enzyme inhibitory activities of methanol and water extracts and gene expression in Hypericum lydium

N Eruygur, E Ucar, HA Akpulat, K Shahsavari… - Molecular biology …, 2019 - Springer
Hypericum lydium Boiss. is a perennial plant of the Hypericaceae family, which has been
used in particular to treat depression. The aim of this study was to determine in vitro …

Dicumarol inhibits PDK1 and targets multiple malignant behaviors of ovarian cancer cells

W Zhang, J Su, H Xu, S Yu, Y Liu, Y Zhang, L Sun… - PloS one, 2017 - journals.plos.org
Pyruvate dehydrogenase kinase 1 (PDK1) is overexpressed in ovarian cancer and thus is a
promising anticancer therapeutic target. Our previous work suggests that coumarin …

The Role of Spirulina (Arthrospira) in the Mitigation of Heavy-Metal Toxicity: An Appraisal

S Bhattacharya - Journal of Environmental Pathology …, 2020 - dl.begellhouse.com
Heavy-metal toxicity imposes a potential worldwide threat to the environment and humans.
Cadmium, mercury, lead, and arsenic are nonessential toxic heavy metals that are most …

A perspective review on impact and molecular mechanism of environmental carcinogens on human health

S Malik, S Prasad, S Kishore, A Kumar… - Biotechnology and …, 2021 - Taylor & Francis
Cancer is one of the leading causes of death all around the world. It is a group of diseases
characterized by abnormal and uncontrollable division of cells leading to severe health …