A Galaxy of informatics resources for MS-based proteomics

S Mehta, M Bernt, M Chambers, M Fahrner… - Expert Review of …, 2023 - Taylor & Francis
Introduction Continuous advances in mass spectrometry (MS) technologies have enabled
deeper and more reproducible proteome characterization and a better understanding of …

Leveraging independent component analysis to unravel transcriptional regulatory networks: A critical review and future directions

Y Zhang, J Zhao, X Sun, Y Zheng, T Chen… - Biotechnology Advances, 2024 - Elsevier
Transcriptional regulatory networks (TRNs) play a crucial role in exploring microbial life
activities and complex regulatory mechanisms. The comprehensive reconstruction of TRNs …

The hallmarks of a tradeoff in transcriptomes that balances stress and growth functions

C Dalldorf, K Rychel, R Szubin, Y Hefner, A Patel… - Msystems, 2024 - journals.asm.org
Fast growth phenotypes are achieved through optimal transcriptomic allocation, in which
cells must balance tradeoffs in resource allocation between diverse functions. One such …

The hallmarks of a tradeoff in transcriptomes that balances stress and growth functions

D Christopher, K Rychel, R Szubin, H Ying, A Patel… - …, 2024 - search.proquest.com
Fast growth phenotypes are achieved through optimal transcriptomic allocation, in which
cells must balance tradeoffs in resource allocation between diverse functions. One such …

Extracellular Respiration is a Latent Energy Metabolism in Escherichia coli

BB Kundu, J Krishnan, R Szubin, A Patel, BO Palsson… - bioRxiv, 2024 - biorxiv.org
Diverse microbial species utilize redox shuttles to exchange electrons with their environment
through mediated extracellular electron transfer (EET). This process maintains redox …

Transcriptome and Redox Proteome Reveal Temporal Scales of Carbon Metabolism Regulation in Model Cyanobacteria Under Light Disturbance

CGM Johnson, Z Johnson, LS Mackey, X Li… - arxiv preprint arxiv …, 2024 - arxiv.org
We develop a systems approach based on an energy-landscape concept to differentiate
interactions involving redox activities and conformational changes of proteins and nucleic …

Predicting microbial transcriptome using genome sequence

BIN SHAO, Y Yan, G FU - bioRxiv, 2024 - biorxiv.org
We present TXpredict, a transformer-based framework for predicting microbial
transcriptomes using annotated genome sequences. By leveraging information learned from …

[ΒΙΒΛΙΟ][B] Understanding transcriptional regulatory mechanisms through data science and modeling

CG Dalldorf - 2024 - search.proquest.com
Transcriptional gene regulation is a primary mechanism that Escherichia coli uses to best
adapt to its current environment. RNA-sequencing data in particular provides us with the …

Integrated Omics Investigation of the Gravitropic Signaling Pathway in Arabidopsis thaliana: Insights From Spaceflight and Ground-Based Experiments

GO Olanrewaju - 2024 - search.proquest.com
Gravity is a fundamental driving force of plant evolution, profoundly influencing numerous
developmental and growth processes in plants. Gravity's most evident impact is the …