Enteric nervous system: sensory transduction, neural circuits and gastrointestinal motility

NJ Spencer, H Hu - Nature reviews Gastroenterology & hepatology, 2020 - nature.com
The gastrointestinal tract is the only internal organ to have evolved with its own independent
nervous system, known as the enteric nervous system (ENS). This Review provides an …

Recent advances in neurotechnologies with broad potential for neuroscience research

A Vázquez-Guardado, Y Yang, AJ Bandodkar… - Nature …, 2020 - nature.com
Interest in deciphering the fundamental mechanisms and processes of the human mind
represents a central driving force in modern neuroscience research. Activities in support of …

Multifunctional microelectronic fibers enable wireless modulation of gut and brain neural circuits

A Sahasrabudhe, LE Rupprecht, S Orguc… - Nature …, 2024 - nature.com
Progress in understanding brain–viscera interoceptive signaling is hindered by a dearth of
implantable devices suitable for probing both brain and peripheral organ neurophysiology …

The preference for sugar over sweetener depends on a gut sensor cell

KL Buchanan, LE Rupprecht, MM Kaelberer… - Nature …, 2022 - nature.com
Guided by gut sensory cues, humans and animals prefer nutritive sugars over non-caloric
sweeteners, but how the gut steers such preferences remains unknown. In the intestine …

Functional circuits and signal processing in the enteric nervous system

C Fung, P Vanden Berghe - Cellular and Molecular Life Sciences, 2020 - Springer
The enteric nervous system (ENS) is an extensive network comprising millions of neurons
and glial cells contained within the wall of the gastrointestinal tract. The major functions of …

Activation of mechanoluminescent nanotransducers by focused ultrasound enables light delivery to deep-seated tissue in vivo

S Jiang, X Wu, F Yang, NJ Rommelfanger, G Hong - Nature protocols, 2023 - nature.com
Light is used extensively in biological and medical research for optogenetic
neuromodulation, fluorescence imaging, photoactivatable gene editing and light-based …

Disorders of the enteric nervous system—a holistic view

B Niesler, S Kuerten, IE Demir… - … reviews Gastroenterology & …, 2021 - nature.com
The enteric nervous system (ENS) is the largest division of the peripheral nervous system
and closely resembles components and functions of the central nervous system. Although …

An ingestible, battery-free, tissue-adhering robotic interface for non-invasive and chronic electrostimulation of the gut

K Nan, K Wong, D Li, B Ying, JC McRae… - Nature …, 2024 - nature.com
Ingestible electronics have the capacity to transform our ability to effectively diagnose and
potentially treat a broad set of conditions. Current applications could be significantly …

Wirelessly powered deformable electronic stent for noninvasive electrical stimulation of lower esophageal sphincter

C Zhang, C Pan, KF Chan, J Gao, Z Yang… - Science …, 2023 - science.org
Electrical stimulation is a promising method to modulate gastrointestinal disorders. However,
conventional stimulators need invasive implantation and removal surgeries associated with …

The enteric nervous system

KA Sharkey, GM Mawe - Physiological reviews, 2023 - journals.physiology.org
Of all the organ systems in the body, the gastrointestinal tract is the most complicated in
terms of the numbers of structures involved, each with different functions, and the numbers …