Stem cells can be defined as units of biological organization that are responsible for the
development and the regeneration of organ and tissue systems. They are able to renew their …

Three dimensional (3D) tissue models of the human skin are probably the most developed
and understood in vitro engineered constructs. The motivation to accomplish organotypic …

Skin is the largest organ of human body, acting as a barrier with protective, immunologic and
sensorial functions. Its permanent exposure to the external environment can result in …

The clinical treatment of large, full-thickness skin injuries with tissue-engineered autologous
dermo–epidermal skin substitutes is an emerging alternative to split-thickness skin grafting …

Collagen is a key component of the extracellular matrix (ECM) in organs and tissues
throughout the body and is used for many tissue engineering applications. Electrospinning …

Mechanical cell stretching may be an attractive strategy for the tissue engineering of
mechanically functional tissues. It has been demonstrated that cell growth and differentiation …

The utilization of materials in medical implants, serving as substitutes for non-functional
biological structures, supporting damaged tissues, or reinforcing active organs, holds …

Tissue engineering (TE) and regenerative medicine are a blend of developmental biology,
life sciences, and engineering efforts that attempts to address clinical problems. Tissue …

This study describes a perfusable and stretchable culture system for a skin-equivalent. The
system is comprised of a flexible culture device equipped with connections that fix vascular …

Tissue engineering scaffolds are commonly formed using proteins extracted from animal
tissues, such as bovine hide. Risks associated with the use of these materials include …