There has been extensive progress in understanding the cellular and molecular
mechanisms of inflammation and immune regulation in allergic diseases of the skin and …

Sepsis results in a deluge of pro-and anti-inflammatory cytokines, leading to lymphopenia
and chronic immunoparalysis. Sepsis-induced long-lasting immunoparalysis is defined, in …

Human natural killer T (NKT) cells have been proposed as a promising cell platform for
chimeric antigen receptor (CAR) therapy in solid tumors. Here we generated murine CAR …

NKT cells are innate-like T cells, recruited to the skin during viral infection, yet their
contributions to long-term immune memory to viruses are unclear. We identified granzyme K …

Mammalian innate-like T cells (ILTCs), including mucosal-associated invariant T (MAIT),
natural killer T (NKT), and γδ T cells, are abundant tissue-resident lymphocytes that have …

Multidomain Peptide (MDP) hydrogels are nanofibrous materials with many potential
biomedical applications. The peptide sequence design of these materials offers high …

Psoriasis is a recurring inflammatory skin condition characterized by scaly, red patches on
the skin. It affects approximately 3% of the US population and is associated with histological …

iNKT cells are a subset of innate-like T cells that utilize an invariant TCR alpha chain
complexed with a limited repertoire of TCR beta chains to recognize specific lipid antigens …

Invariant natural killer T (iNKT) cells are a CD1d-restricted T cell population that can respond
to lipid antigenic stimulation within minutes by secreting a wide variety of cytokines. This …

Summary Two doses of Pfizer/BioNTech BNT162b2 mRNA vaccine elicit robust severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing antibodies with …