Research progress in pharmacological activities and structure-activity relationships of tetralone scaffolds as pharmacophore and fluorescent skeleton
K Sheng, Y Song, F Lei, W Zhao, L Fan, L Wu… - European journal of …, 2022 - Elsevier
The tetralone and tetralone derivatives, as crucial structural scaffolds of potential novel
drugs targeted at multiple biological end-points, are normally found in several natural …
drugs targeted at multiple biological end-points, are normally found in several natural …
Chemically engineered exogenous organic reactions in living cells for in situ fluorescence imaging and biomedical applications
The unique microenvironment within living cells, characterized by high glutathione levels,
reactive oxygen species concentrations, and active enzymes, facilitates the execution of …
reactive oxygen species concentrations, and active enzymes, facilitates the execution of …
Bioactivity of selenium‐containing pyridinium salts: Prospecting future pharmaceutical constituents to treat liver diseases involving oxidative stress
ET Castro, AG Alves… - … of Biochemical and …, 2024 - Wiley Online Library
Redox imbalance leads to oxidative stress that causes irreversible cellular damage. The
incorporation of the antioxidant element selenium (Se) in the structure of pyridinium salts …
incorporation of the antioxidant element selenium (Se) in the structure of pyridinium salts …
Fluorescent probes for detecting and imaging mitochondrial hydrogen sulfide
YW Zhu, EE Ngowi, AQ Tang, T Chu, Y Wang… - Chemico-Biological …, 2025 - Elsevier
Hydrogen sulfide (H 2 S) is a potent redox-active signaling molecule commonly
dysregulated in disease states. The production of H 2 S and its involvement in various …
dysregulated in disease states. The production of H 2 S and its involvement in various …
Synthesis of CuI-modified thiol-functionalized MCM-41 silica-based materials and their catalytic tetralin performance
C Wu, Y Li, Y Ma, Y Lei, M Wang, Z Chen - Journal of Porous Materials, 2024 - Springer
A novel loaded copper ion catalyst, Cu/MCM-41-SH, was synthesized using CuI-modified
thiol-functionalized MCM-41 silica-based materials, and the prepared catalysts were …
thiol-functionalized MCM-41 silica-based materials, and the prepared catalysts were …
Design and synthesis of novel tetrabromophthalimide derivatives as potential tubulin inhibitors endowed with apoptotic induction for cancer treatment
Although various approaches exist for treating cancer, chemotherapy continues to hold a
prominent role in the management of this disease. Besides, microtubules serve as a vital …
prominent role in the management of this disease. Besides, microtubules serve as a vital …
[PDF][PDF] Synthesis and biological evaluation of some new imidazo [1, 2-c] pyrimido [5, 4-e] pyrimidin-5-amine derivatives.
RJ Obaid - Umm Al-Qura University Journal of Applied Sciences, 2021 - researchgate.net
The pyrimidine ring is a skeleton of particular interest that it is present in many compounds
exhibiting biological and pharmaceutical activity. In the present work, some new pyrimidine …
exhibiting biological and pharmaceutical activity. In the present work, some new pyrimidine …
A series of D-π-A and A-π-A'fluorescent probes were used to explore the influence of terminal groups on the properties of the hemicyanine probes
W Sun, G Hu, W Shen, H Xu, Z Deng, G Zhao… - Journal of Molecular …, 2021 - Elsevier
Based on the addition reaction of sulfur dioxide derivatives and Cdouble bondC, a series of
D-π-A and A-π-A'fluorescent probes were designed by combining different electronic groups …
D-π-A and A-π-A'fluorescent probes were designed by combining different electronic groups …
Polymethine cyanine dyes: Synthesis, cytotoxic activity, and molecular docking study
AA Fadda, ER El-Sawy, RE El-Mekawy - Journal of Molecular Structure, 2023 - Elsevier
Virtually, an efficient synthetic procedure was adapted to synthesize new methine cyanine
dyes 3–22 from N-arenium salt 2 which was synthesized from the reaction of 1, 6 …
dyes 3–22 from N-arenium salt 2 which was synthesized from the reaction of 1, 6 …
Role of enaminonitriles in heterocyclic synthesis: synthesis of some new aminothiazole derivatives against prostate carcinoma
Among sulfur-and nitrogen-containing heterocyclic compounds, the aminothiazole scaffold
is one of the most unique architectures in drug development, since it comprises a variety of …
is one of the most unique architectures in drug development, since it comprises a variety of …