Exosomal microRNAs derived from mesenchymal stem cells: cell-to-cell messages

K Asgarpour, Z Shojaei, F Amiri, J Ai… - Cell Communication and …, 2020 - Springer
Exosomes are extracellular vesicles characterized by their size, source, release mechanism
and contents. MicroRNAs (miRNAs) are single stranded non-coding RNAs transcribed from …

MicroRNA: A novel target of curcumin in cancer therapy

H Mirzaei, A Masoudifar, A Sahebkar… - Journal of cellular …, 2018 - Wiley Online Library
Curcumin is known as a natural dietary polyphenol which is extracted from Curcuma longa
L. It has been shown that curcumin has a variety of pharmacological effects such as …

Curcumin reinforces MSC‐derived exosomes in attenuating osteoarthritis via modulating the miR‐124/NF‐kB and miR‐143/ROCK1/TLR9 signalling pathways

B Qiu, X Xu, P Yi, Y Hao - Journal of Cellular and Molecular …, 2020 - Wiley Online Library
Curcumin treatment was reported to delay the progression of OA, but its underlying
mechanism remains unclear. In this study, we aimed to investigate the molecular …

Emerging delivery approaches for targeted pulmonary fibrosis treatment

R Diwan, HN Bhatt, E Beaven, M Nurunnabi - Advanced drug delivery …, 2024 - Elsevier
Pulmonary fibrosis (PF) is a progressive, and life-threatening interstitial lung disease which
causes scarring in the lung parenchyma and thereby affects architecture and functioning of …

Stem cell therapy: a new therapeutic option for cardiovascular diseases

NH Goradel, FG Hour, B Negahdari… - Journal of cellular …, 2018 - Wiley Online Library
Cardiovascular diseases are known as one of major causes of morbidity and mortality
worldwide. Despite the many advancement in therapies are associated with cardiovascular …

Nanoparticles as new tools for inhibition of cancer angiogenesis

N Hashemi Goradel, F Ghiyami‐Hour… - Journal of cellular …, 2018 - Wiley Online Library
Angiogenesis is known as one of the hallmarks of cancer. Multiple lines evidence indicated
that vascular endothelium growth factor (VEGF) is a key player in the progression of …

Stem cell-based therapy for pulmonary fibrosis

W Cheng, Y Zeng, D Wang - Stem Cell Research & Therapy, 2022 - Springer
Pulmonary fibrosis (PF) is a chronic and relentlessly progressive interstitial lung disease in
which the accumulation of fibroblasts and extracellular matrix (ECM) induces the destruction …

Molecular mechanisms and clinical application of multipotent stem cells for spinal cord injury

M Szymoniuk, J Litak, L Sakwa, A Dryla, W Zezuliński… - Cells, 2022 - mdpi.com
Spinal Cord Injury (SCI) is a common neurological disorder with devastating psychical and
psychosocial sequelae. The majority of patients after SCI suffer from permanent disability …

MiR‐21: A key player in glioblastoma pathogenesis

MS Masoudi, E Mehrabian… - Journal of cellular …, 2018 - Wiley Online Library
Glioblastoma multiform (GBM) is one of common cancers worldwide which has high rate
among various populations. Despite serious efforts worldwide, GBM remains a deadly …

TGF-β1-modified MSC-derived exosomal miR-135b attenuates cartilage injury via promoting M2 synovial macrophage polarization by targeting MAPK6

R Wang, B Xu - Cell and tissue research, 2021 - Springer
Osteoarthritis (OA) is the most common joint disease with an unsatisfactory therapy outcome
and characterized by the degradation of articular cartilage and synovial inflammation. Here …