The Martini model, a coarse‐grained force field for molecular dynamics simulations, has
been around for nearly two decades. Originally developed for lipid‐based systems by the …

Recent studies have revealed that cancer cell-derived extracellular vesicles (EVs) modulate
immunological responses. Lipids have diverse biological functions, and are known to …

Molecular dynamics simulations are now widely used to study emergent phenomena in lipid
membranes with complex compositions. Here, we present LiPyphilic—a fast, fully tested …

The proposition of a post-antimicrobial era is all the more realistic with the continued rise of
antimicrobial resistance. The development of new antimicrobials is failing to counter the ever …

The World Health Organization has identified multidrug-resistant bacteria as a serious
global health threat. Gram-negative bacteria are particularly prone to antibiotic resistance …

Exogenous polyunsaturated fatty acids (PUFAs) are readily incorporated into the synthesis
pathways of A. baumannii membrane phospholipids, where they contribute to reduced …

Abstract P2X7 receptors (P2X7Rs) are membrane-bound ATP-gated ion channels that are
composed of three subunits. Different subunit structures may be expressed due to …

Cholesterol is integral to the structure of mammalian cell membranes. Oxidation of
cholesterol alters how it behaves in the membrane and influences the membrane …

The occurrence of linear cholesterol-recognition motifs in alpha-helical transmembrane
domains has long been debated. Here, we demonstrate the ability of a genetic algorithm …

The Gram-negative pathogen Acinetobacter baumannii is a primary contributor to
nosocomial multi-drug-resistant (MDR) infections. To combat the rise of MDR infections …